INT108913

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Context Info
Confidence 0.28
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 5.71
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HAL) small molecule metabolic process (HAL) lyase activity (HAL)
biosynthetic process (HAL) cellular nitrogen compound metabolic process (HAL) cytoplasm (HAL)
Anatomy Link Frequency
lens 2
tube 1
femur 1
HAL (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 41 99.92 Very High Very High Very High
Potency 1 98.22 Very High Very High Very High
Sciatica 2 90.76 High High
bradykinin 3 87.68 High High
qutenza 4 87.08 High High
nociceptor 4 82.68 Quite High
Serotonin 2 80.04 Quite High
c fibre 2 75.00 Quite High
Spinal cord 6 65.28 Quite High
imagery 11 62.28 Quite High
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 1 100.00 Very High Very High Very High
Pain 34 99.92 Very High Very High Very High
Injury 118 99.18 Very High Very High Very High
Suicidal Behaviour 129 98.92 Very High Very High Very High
Muscle Weakness 1 98.24 Very High Very High Very High
Infection 31 95.08 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 85 94.68 High High
Muscle Disease 3 93.24 High High
Gunshot Wounds 9 93.00 High High
Nerve Root Compression 4 90.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that CMi(His+) units are "selective," but not "specific" for pruritogenic substances and that the pruritic potency of a mediator increases with its ability to activate CMi(His+) units but decreases with activation of CMH and CMi(His-) units.
Positive_regulation (activation) of His associated with potency
1) Confidence 0.28 Published 2003 Journal J. Neurophysiol. Section Abstract Doc Link 12611975 Disease Relevance 0.51 Pain Relevance 0.98
Even in the best-case scenario, all that Harry's clinicians can hope for is a 'stabilization' of his status, with the eventual placement of a tracheostomy and feeding tube with lifelong care and residence in a nursing home.
Positive_regulation (stabilization) of his in tube
2) Confidence 0.14 Published 2001 Journal Crit Care Section Body Doc Link PMC137271 Disease Relevance 0.50 Pain Relevance 0.09
It has been suggested by consultants that Harry might have changed his mind and desires us to continue his suffering, and cannot tell us his wishes.
Positive_regulation (changed) of his
3) Confidence 0.14 Published 2001 Journal Crit Care Section Body Doc Link PMC137271 Disease Relevance 0.23 Pain Relevance 0.17
Instead of ending his life and alleviating his 'pain' as detailed in his suicide note, an opposite - almost unimaginable - course of action occurred.
Positive_regulation (alleviating) of his associated with pain and suicidal behaviour
4) Confidence 0.14 Published 2001 Journal Crit Care Section Body Doc Link PMC137271 Disease Relevance 0.49 Pain Relevance 0.10
He received 1 liter of LR with an increase of his BP to 110/70 mm Hg and StO2 to 82%.
Positive_regulation (increase) of his
5) Confidence 0.06 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2714076 Disease Relevance 0.79 Pain Relevance 0
Just as Platter made “observations” of the symptoms of goitrous foolishness which “I myself saw” through the lens of an existing paradigm, influenced partly by melancholy and partly by perceptions of social status, D'Alembert saw in the same population his own, quite different symptoms through the lens of Locke's Essay.58 To the brief extent (one sentence in a heavy tome) that Platter appears to single out certain Alpine people from the poorer peasantry in general or from those exhibiting the other symptoms listed above, he nevertheless keeps the same elastic term stulti for all of them.59
Positive_regulation (population) of his in lens
6) Confidence 0.06 Published 2004 Journal Medical History Section Body Doc Link PMC547918 Disease Relevance 0.09 Pain Relevance 0
Just as Platter made “observations” of the symptoms of goitrous foolishness which “I myself saw” through the lens of an existing paradigm, influenced partly by melancholy and partly by perceptions of social status, D'Alembert saw in the same population his own, quite different symptoms through the lens of Locke's Essay.58 To the brief extent (one sentence in a heavy tome) that Platter appears to single out certain Alpine people from the poorer peasantry in general or from those exhibiting the other symptoms listed above, he nevertheless keeps the same elastic term stulti for all of them.59
Positive_regulation (saw) of his in lens
7) Confidence 0.06 Published 2004 Journal Medical History Section Body Doc Link PMC547918 Disease Relevance 0.09 Pain Relevance 0
He received debridement and progressive closure of his wound every other day and 10 days post-injury received intramedullary femoral rod for stabilization of his femur fracture.
Positive_regulation (stabilization) of his in femur associated with injury
8) Confidence 0.04 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2714076 Disease Relevance 0.37 Pain Relevance 0
His StO2 increased to 88%.
Positive_regulation (increased) of His
9) Confidence 0.04 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2714076 Disease Relevance 0.62 Pain Relevance 0
His CD4+ cell count was 465 cells/mcL and his creatine phosphokinase (CPK) enzyme levels were highly elevated.
Positive_regulation (elevated) of his creatine phosphokinase associated with disorders of creatine metabolism
10) Confidence 0.01 Published 2005 Journal J Int AIDS Soc Section Body Doc Link PMC2740789 Disease Relevance 2.03 Pain Relevance 0.25

General Comments

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