INT108936

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Context Info
Confidence 0.41
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Arrb2) cytoplasmic membrane-bounded vesicle (Arrb2) plasma membrane (Arrb2)
nucleus (Arrb2) intracellular (Arrb2) cytoplasm (Arrb2)
Anatomy Link Frequency
hippocampus 2
Arrb2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 2 99.40 Very High Very High Very High
Morphine 10 98.90 Very High Very High Very High
withdrawal 1 98.66 Very High Very High Very High
narcan 1 98.18 Very High Very High Very High
opiate 1 93.44 High High
cerebral cortex 3 91.20 High High
Central grey 3 89.60 High High
Locus ceruleus 2 80.00 Quite High
Opioid 1 65.76 Quite High
tolerance 2 65.20 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 3 89.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, spontaneous or naloxone-precipitated withdrawal of morphine that did not affect the level of beta-arrestin 1 mRNA resulted in an aberrant increase (100% over control) in beta-arrestin 2 mRNA level in hippocampus.
Positive_regulation (resulted) of Positive_regulation (increase) of beta-arrestin 2 in hippocampus associated with narcan, hippocampus, withdrawal and morphine
1) Confidence 0.41 Published 2003 Journal Neuroscience Section Abstract Doc Link 12614678 Disease Relevance 0.25 Pain Relevance 1.40

General Comments

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