INT108985

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Context Info
Confidence 0.43
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Gdnf) extracellular space (Gdnf) extracellular region (Gdnf)
Gdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 3 99.36 Very High Very High Very High
Hyperalgesia 3 96.04 Very High Very High Very High
Pain 8 90.20 High High
Arthritis 1 83.12 Quite High
Lasting pain 1 78.80 Quite High
Dorsal horn 1 72.20 Quite High
Spinal cord 2 71.72 Quite High
IPN 1 59.04 Quite High
Nerve growth factor 1 46.08 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 99.36 Very High Very High Very High
Hyperalgesia 3 96.04 Very High Very High Very High
Pain 6 90.20 High High
Arthritis 1 83.12 Quite High
Inflammatory Pain 1 59.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of this antibody coincided with the down-regulation of GDNF immunoreactivity in response to inflammation, suggesting that GDNF supports biochemical changes that contribute to hyperalgesia.
Negative_regulation (down-regulation) of Regulation (immunoreactivity) of GDNF associated with hyperalgesia and inflammation
1) Confidence 0.43 Published 2003 Journal Neuroscience Section Abstract Doc Link 12617957 Disease Relevance 1.11 Pain Relevance 1.04

General Comments

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