INT10901

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Context Info
Confidence 0.39
First Reported 1992
Last Reported 1992
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.68
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1, Nppb) extracellular region (Edn1, Nppb) cytoplasm (Edn1, Nppb)
nucleus (Nppb) cell-cell signaling (Edn1)
Anatomy Link Frequency
blood 2
cardiocytes 2
Edn1 (Rattus norvegicus)
Nppb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 3 99.40 Very High Very High Very High
Natriuresis 6 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations indicate that AVP, AII and ET-1 stimulate the release of ir-BNP (probably rat BNP-45) through a change in blood pressure.
ET-1 Positive_regulation (stimulate) of Localization (release) of BNP in blood associated with cv unclassified under development
1) Confidence 0.39 Published 1992 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 1526063 Disease Relevance 0.23 Pain Relevance 0
In addition, ET-1 may also induce ir-BNP release through direct stimulation.
ET-1 Spec (may) Positive_regulation (induce) of Localization (release) of BNP
2) Confidence 0.39 Published 1992 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 1526063 Disease Relevance 0.23 Pain Relevance 0
ET-1 clearly stimulated the secretion of ir-BNP in both atrial and ventricular cardiocytes.
ET-1 Positive_regulation (stimulated) of Localization (secretion) of BNP in cardiocytes
3) Confidence 0.39 Published 1992 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 1526063 Disease Relevance 0.22 Pain Relevance 0

General Comments

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