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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NKX2-5) extracellular region (Pdyn) nucleus (NKX2-5)
plasma membrane (Pdyn) DNA binding (NKX2-5) transcription factor binding (NKX2-5)
Anatomy Link Frequency
embryonic cells 2
Pdyn (Rattus norvegicus)
NKX2-5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 2 100.00 Very High Very High Very High
Kappa opioid receptor 1 80.24 Quite High
Kinase C 15 77.44 Quite High
opioid receptor 2 63.76 Quite High
Enkephalin 2 25.00 Low Low
antagonist 1 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The prodynorphin gene and its product, dynorphin B, have been found to promote cardiogenesis in embryonic cells by inducing the expression of GATA-4 and Nkx-2.5, two transcription factor-encoding genes essential for cardiogenesis.
prodynorphin gene Positive_regulation (inducing) of Gene_expression (expression) of Nkx-2.5 in embryonic cells associated with dynorphin
1) Confidence 0.01 Published 2003 Journal Circ. Res. Section Abstract Doc Link 12623877 Disease Relevance 0 Pain Relevance 0.29

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