INT109074

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Context Info
Confidence 0.69
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NKX2-5) nucleus (NKX2-5) DNA binding (NKX2-5)
transcription factor binding (NKX2-5) cytoplasm (NKX2-5)
NKX2-5 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 99.14 Very High Very High Very High
Kappa opioid receptor 2 98.98 Very High Very High Very High
Dynorphin 9 97.98 Very High Very High Very High
Opioid 1 81.12 Quite High
opioid receptor 4 80.88 Quite High
antagonist 2 79.60 Quite High
Kinase C 7 75.00 Quite High
Enkephalin 2 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Direct exposure of nuclei isolated from undifferentiated ES cells to dynorphin B or U-50,488H, a synthetic kappa opioid receptor agonist, time- and dose-dependently activated the transcription of GATA-4 and Nkx-2.5, 2 cardiac lineage-promoting genes.
Transcription (transcription) of Nkx-2.5 associated with dynorphin, agonist and kappa opioid receptor
1) Confidence 0.69 Published 2003 Journal Circ. Res. Section Abstract Doc Link 12623878 Disease Relevance 0 Pain Relevance 1.01

General Comments

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