INT109097

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Context Info
Confidence 0.05
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.19
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GGT5) plasma membrane (GGT5) transferase activity, transferring acyl groups (GGT5)
cellular amino acid metabolic process (GGT5)
GGT5 (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 1 99.32 Very High Very High Very High
abdominal pain 1 95.76 Very High Very High Very High
pruritus 1 81.08 Quite High
Disease Link Frequency Relevance Heat
Syndrome 2 99.96 Very High Very High Very High
Favism 1 99.68 Very High Very High Very High
Headache 1 99.32 Very High Very High Very High
Convulsion 1 98.70 Very High Very High Very High
Coma 1 98.38 Very High Very High Very High
Liver Failure 1 96.00 Very High Very High Very High
Abdominal Pain 1 95.76 Very High Very High Very High
Vomiting 2 94.60 High High
Anaphylaxis 2 89.52 High High
Urticaria 1 81.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hepatobiliary involvement was reported 25 times, including increases in alkaline phosphatase, gamma-glutamyltransferase, and alanine and aspartate aminotransferase levels.
Positive_regulation (increases) of Gene_expression (levels) of gamma-glutamyltransferase
1) Confidence 0.05 Published 2006 Journal Drug Saf Section Abstract Doc Link 17061910 Disease Relevance 1.62 Pain Relevance 0.14
Reported adverse effects of bitter melon include hypoglycemic coma and convulsions in children, reduced fertility in mice, a favism-like syndrome, increases in gamma-glutamyltransferase and alkaline phosphatase levels in animals, and headaches.
Positive_regulation (increases) of Gene_expression (levels) of gamma-glutamyltransferase associated with convulsion, syndrome, favism, headache and coma
2) Confidence 0.04 Published 2003 Journal Am J Health Syst Pharm Section Abstract Doc Link 12625217 Disease Relevance 0.58 Pain Relevance 0.10

General Comments

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