INT109142

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Calca, Creb1) nucleoplasm (Creb1) mitochondrion (Creb1)
aging (Calca) intracellular (Calca) DNA binding (Creb1)
Anatomy Link Frequency
neurons 2
Calca (Rattus norvegicus)
Creb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 12 100.00 Very High Very High Very High
antagonist 1 99.48 Very High Very High Very High
substance P 3 96.60 Very High Very High Very High
Inflammation 1 65.92 Quite High
Spinal cord 1 64.68 Quite High
Hyperalgesia 1 62.52 Quite High
Neuropeptide 1 60.56 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 65.92 Quite High
Hyperalgesia 1 62.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CGRP increased phosphorylated CREB immunoreactivity and CRE-dependent transcription in neurons, indicating the involvement of the transcription factor CREB.
CGRP Positive_regulation (increased) of Transcription (transcription) of CREB in neurons associated with calcitonin gene-related peptide
1) Confidence 0.47 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12629185 Disease Relevance 0.13 Pain Relevance 0.80

General Comments

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