INT10924

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Context Info
Confidence 0.04
First Reported 1984
Last Reported 2006
Negated 2
Speculated 1
Reported most in Abstract
Documents 25
Total Number 26
Disease Relevance 11.12
Pain Relevance 7.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 9
heart 5
urine 2
plasma 1
brain 1
Sysbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 70 100.00 Very High Very High Very High
anesthesia 20 99.74 Very High Very High Very High
epidural 7 99.64 Very High Very High Very High
lidocaine 2 99.60 Very High Very High Very High
Thoracotomy 6 99.38 Very High Very High Very High
qutenza 7 99.16 Very High Very High Very High
Dopamine 9 98.90 Very High Very High Very High
halothane 6 98.24 Very High Very High Very High
ischemia 5 97.52 Very High Very High Very High
isoflurane 8 97.12 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 70 100.00 Very High Very High Very High
Pneumoperitoneum 7 99.64 Very High Very High Very High
Hypotension 6 99.60 Very High Very High Very High
Pressure Volume 2 Under Development 10 99.44 Very High Very High Very High
Bradycardia 5 99.42 Very High Very High Very High
Peripheral Arterial Disease 4 99.40 Very High Very High Very High
Renal Failure 3 99.28 Very High Very High Very High
Pressure And Volume Under Development 11 99.12 Very High Very High Very High
Hypertension 45 98.84 Very High Very High Very High
Stress 2 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Baseline systolic blood pressure (SBP) and mean BP increased significantly with age (R = 0.81, P less than 0.001 and R = 0.76, P less than 0.001, respectively) but age was not significantly related to increases in SBP and mean BP following intubation.
Positive_regulation (increased) of systolic blood pressure in blood
1) Confidence 0.04 Published 1989 Journal Anesth. Analg. Section Abstract Doc Link 2541638 Disease Relevance 0.17 Pain Relevance 0.09
Prostenon, having a modulating effect on the cardiovascular system, induces an increase in mean blood pressure (MBP) in hypotensive patients and a decrease in MBP in hypertensive patients, lowers SI and ITC and elevates HR, CI and RC.
Positive_regulation (increase) of mean blood pressure in blood associated with hypertension and hypotension
2) Confidence 0.02 Published 1989 Journal Anesteziol Reanimatol Section Abstract Doc Link 2802250 Disease Relevance 0.29 Pain Relevance 0.50
In animals with intact baroreceptors, intra-arterial injection of capsaicin (4 +/- 1 microgram) produced significant increases in mean blood pressure (MBP) and heart rate (HR) by +43 +/- 8 mmHg and +33 +/- 15 beats/min at 20 s after the injection, respectively.
Positive_regulation (increases) of mean blood pressure in heart associated with qutenza
3) Confidence 0.01 Published 1990 Journal Jpn. J. Physiol. Section Abstract Doc Link 2077174 Disease Relevance 0 Pain Relevance 0.27
Two methods of testing the arterial baroreceptor reflex were used: steady-state increases in PI evoked in response to maintained step increases in systolic arterial blood pressure (SABP) from inflation of an aortic balloon-tipped catheter, and beat-by-beat increases in PI evoked reflexly by 'ramp' increases in blood pressure caused by intravenous injections of phenylephrine.
Positive_regulation (increases) of systolic arterial blood pressure in blood associated with pressure and volume under development
4) Confidence 0.01 Published 1992 Journal J. Auton. Nerv. Syst. Section Abstract Doc Link 1527350 Disease Relevance 0.10 Pain Relevance 0.08
Mean (+/- SEM) BS in awake horses was 28.9 +/- 2.6 and 13.2 +/- 2.0 ms/mm of Hg during steady-state decreases and increases in systolic arterial pressure (SAP), respectively.
Positive_regulation (increases) of systolic arterial pressure
5) Confidence 0.01 Published 1989 Journal Am. J. Vet. Res. Section Abstract Doc Link 2610441 Disease Relevance 0 Pain Relevance 0.43
All three drugs dose-dependently reduced both the increase in IUP and the mean blood pressure (MBP).
Positive_regulation (increase) of mean blood pressure in blood
6) Confidence 0.01 Published 2006 Journal Yakugaku Zasshi Section Abstract Doc Link 16518087 Disease Relevance 0.43 Pain Relevance 0.20
After the first four weeks of monotherapy respectively double-combination therapy (V3), patients will be reassessed for compliance, adverse events and supplied with medication for the next eight weeks (except for the monotherapy patients who reached goal blood pressure and who will terminate the study).
Neg (except) Positive_regulation (reached) of goal blood pressure in blood
7) Confidence 0.01 Published 2004 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC524514 Disease Relevance 0.07 Pain Relevance 0
At this maximum class III dose, azimilide increased heart contractile force (HCF) 10% and +dP/dt 34% and decreased heart rate (HR) 12%, without significantly changing mean blood pressure (MBP), left ventricular end diastolic pressure, -dP/dt, stroke volume (SV), or cardiac output (CO).
Neg (without) Positive_regulation (changing) of mean blood pressure in heart associated with stroke and bradycardia
8) Confidence 0.00 Published 2000 Journal Arzneimittelforschung Section Abstract Doc Link 10965415 Disease Relevance 0.48 Pain Relevance 0
OBJECTIVES: To compare the preventive effects of esmolol and lidocaine on the increase in mean arterial pressure (MAP) and intracranial pressure (ICP) during endotracheal intubation in neurosurgery.
Positive_regulation (increase) of intracranial pressure associated with cva and lidocaine
9) Confidence 0.00 Published 1996 Journal Ann Fr Anesth Reanim Section Abstract Doc Link 8729308 Disease Relevance 0.25 Pain Relevance 0.26
In anesthetized closed- and open-chest dogs, NP-252 (i.v.) selectively increased vertebral and coronary blood flow with a fall in mean blood pressure (MBP).
Positive_regulation (increased) of mean blood pressure in chest
10) Confidence 0.00 Published 1992 Journal Arzneimittelforschung Section Abstract Doc Link 1530674 Disease Relevance 0.08 Pain Relevance 0.04
Both aversive brain stimulation or foot-shocks applied at threshold intensities caused running or jumps concomitant with increases in mean arterial blood pressure (MBP) and heart rate (HR).
Positive_regulation (increases) of mean arterial blood pressure in heart associated with shock
11) Confidence 0.00 Published 1990 Journal Neurosci Biobehav Rev Section Abstract Doc Link 2287487 Disease Relevance 0.54 Pain Relevance 0.69
Whether succinylcholine causes an increase in intracranial pressure (ICP) in patients with brain lesions is uncertain and, if increased ICP does occur, its pathophysiology remains unknown.
Spec (Whether) Positive_regulation (increase) of intracranial pressure in brain associated with cva
12) Confidence 0.00 Published 1986 Journal Anesthesiology Section Abstract Doc Link 2874752 Disease Relevance 0.61 Pain Relevance 0.33
Increases in intracranial pressure from succinylcholine: prevention by prior nondepolarizing blockade.
Positive_regulation (Increases) of intracranial pressure associated with cva
13) Confidence 0.00 Published 1986 Journal Anesthesiology Section Title Doc Link 2874752 Disease Relevance 0.82 Pain Relevance 0.44
JTV-506 (2.5-10 microg/kg, i.v.) elicited dose-dependent increases in coronary blood flow (CBF) and heart rate (HR) but only slight changes in mean blood pressure (MBP).
Positive_regulation (increases) of mean blood pressure in blood
14) Confidence 0.00 Published 1997 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9125679 Disease Relevance 0 Pain Relevance 0.05
Baseline mean blood pressure (MBP), plasma norepinephrine (NE), plasma renin activity (PRA) and aldosterone were elevated in patients with renal failure.
Positive_regulation (elevated) of mean blood pressure in plasma associated with renal failure
15) Confidence 0.00 Published 1984 Journal Nephron Section Abstract Doc Link 6361595 Disease Relevance 0.78 Pain Relevance 0.38
Blood loss tended to increase with an increase in intraabdominal pressure in the narrow pad support width of the Wilson frame.
Positive_regulation (increase) of intraabdominal pressure in Blood associated with pressure volume 2 under development and peripheral arterial disease
16) Confidence 0.00 Published 2000 Journal Anesth. Analg. Section Abstract Doc Link 10960374 Disease Relevance 0.98 Pain Relevance 0.06
Intravenous infusion of dopamine (10-100 micrograms/kg/min) resulted in a dose-related increase in mean blood pressure (MBP), urine output, sodium excretion (UNaV), and fractional sodium excretion (FENa).
Positive_regulation (increase) of mean blood pressure in urine associated with dopamine
17) Confidence 0.00 Published 1991 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 1709232 Disease Relevance 0.07 Pain Relevance 0.30
Initially, the mean blood pressure (MBP) increased followed by a precipitate decrease at a mean dose of 2.03 +/- 0.5 mg/kg of cocaine.
Positive_regulation (increased) of mean blood pressure in blood associated with cocaine
18) Confidence 0.00 Published 1998 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9676719 Disease Relevance 0.36 Pain Relevance 0.51
Maintenance of orotracheal tube intra-cuff pressure (IcP) in a range preventing aspiration and avoiding tracheal ischemia is one way to enhance patient safety.
Positive_regulation (Maintenance) of intra-cuff pressure in tube associated with ischemia
19) Confidence 0.00 Published 1995 Journal CRNA Section Abstract Doc Link 7633347 Disease Relevance 0.10 Pain Relevance 0.21
The former condition markedly increased intracranial pressure (ICP), whereas the latter only slightly reduced ICP.
Positive_regulation (increased) of intracranial pressure associated with cva
20) Confidence 0.00 Published 2004 Journal J. Neurophysiol. Section Abstract Doc Link 15056689 Disease Relevance 0.64 Pain Relevance 0.27

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