INT109333

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Context Info
Confidence 0.42
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.71
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (SOD2) oxidoreductase activity (SOD2) aging (SOD2)
mitochondrion organization (SOD2) DNA binding (SOD2) cytoplasm (SOD2)
Anatomy Link Frequency
MIA PaCa-2 2
SOD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
diclofenac 80 99.88 Very High Very High Very High
Chronic pancreatitis 1 40.92 Quite Low
cINOD 9 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 91.96 High High
Lung Cancer 1 89.20 High High
Pancreatic Cancer 5 84.52 Quite High
Adenocarcinoma 1 75.00 Quite High
Apoptosis 44 62.48 Quite High
Neuroblastoma 10 50.00 Quite Low
Pancreatitis 1 40.92 Quite Low
Parkinson's Disease 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M diclofenac, the SOD2 protein level was significantly reduced.
Negative_regulation (reduced) of Gene_expression (level) of SOD2 protein associated with diclofenac
1) Confidence 0.42 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896885 Disease Relevance 0.21 Pain Relevance 0.24
Enforced expression of MnSOD by adenovirus transfection in the rapid growing cell line MIA PaCa-2 increased MnSOD immunoreactivity and MnSOD activity and decreased growth rate.
Negative_regulation (decreased) of Gene_expression (expression) of MnSOD in MIA PaCa-2
2) Confidence 0.41 Published 2003 Journal Cancer Res. Section Abstract Doc Link 12649190 Disease Relevance 0.50 Pain Relevance 0

General Comments

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