INT109475

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grid2) molecular_function (Grid2) biological_process (Grid2)
Anatomy Link Frequency
dendrites 1
synapse 1
Grid2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 4 100.00 Very High Very High Very High
tetrodotoxin 2 76.56 Quite High
withdrawal 2 68.28 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the adult cerebellum, the glutamate receptor delta2 subunit (GluRdelta2) is selectively targeted to the spines of the distal Purkinje cell dendrites, the spiny branchlets, that are innervated by the parallel fibers.
glutamate receptor delta2 subunit Binding (targeted) of in dendrites associated with glutamate receptor
1) Confidence 0.47 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12657696 Disease Relevance 0 Pain Relevance 0.16
We propose instead that GluRdelta2s are associated with climbing fiber-to-Purkinje cell synapses, during development or at early stages of climbing fiber regeneration or sprouting, and are downregulated during the process of synapse maturation.
GluRdelta2s Binding (associated) of in synapse
2) Confidence 0.30 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12657696 Disease Relevance 0 Pain Relevance 0.12

General Comments

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