INT10977

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Context Info
Confidence 0.34
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ENPP3)
Anatomy Link Frequency
basophils 2
ENPP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 66.52 Quite High
Kinase C 17 44.00 Quite Low
anesthesia 1 25.00 Low Low
agonist 7 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 14 67.00 Quite High
INFLAMMATION 6 66.52 Quite High
Myocardial Infarction 2 30.80 Quite Low
Hypertension 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Disease Susceptibility 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low
Anaphylaxis 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quercetin inhibited the expression of CD63 and CD203c and the histamine release in basophils activated with anti-IgE or with the ionophore: the IC50 in the anti-IgE model was higher than in the ionophore model and the effects were more pronounced for CD63 than for CD203c.
Negative_regulation (inhibited) of Gene_expression (expression) of CD203c in basophils
1) Confidence 0.34 Published 2010 Journal Clin Mol Allergy Section Abstract Doc Link PMC2949734 Disease Relevance 0.13 Pain Relevance 0.03
R 80122 is a newly synthesized, selective phosphodiesterase III inhibitor.
Negative_regulation (inhibitor) of Gene_expression (synthesized) of phosphodiesterase III
2) Confidence 0.02 Published 1992 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 1530374 Disease Relevance 0 Pain Relevance 0

General Comments

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