INT10984

Context Info Confidence 0.35 First Reported 1992 Last Reported 1996 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.70 Pain Relevance 0.19

lipid binding (Apoa2) protein folding (Apoa2) transport (Apoa2) extracellular space (Apoa2) extracellular region (Apoa2) cellular_component (Apoa2)

Apoa2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat anesthesia 2 97.20

Disease Link Frequency Relevance Heat Injury 6 100.00 Wound Healing 3 93.52

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Specific binding of 125I-AII was significantly decreased at 12, 18 and 24 hours in the wounded tissue compared to control tissue from the same rat.

Negative_regulation (decreased) of AII Binding (binding) of

1) Confidence 0.35 Published 1992 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 1530605 Disease Relevance 0.17 Pain Relevance 0.10

The levels of 125I-Sar1.Ile8-AII bound to membrane preparations of the wound tissues decreased at early time points (from 0.5 to 4 h), increased from day 1 to day 7, and returned to nonsurgical levels by day 10.

Negative_regulation (decreased) of Ile8-AII Binding (bound) of associated with injury

2) Confidence 0.24 Published 1996 Journal J Invest Surg Section Abstract Doc Link 8981218 Disease Relevance 0.53 Pain Relevance 0.09

General Comments

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