INT109880

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Context Info
Confidence 0.12
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.12
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F8) oxidoreductase activity (F8) extracellular region (F8)
cell adhesion (F8)
Anatomy Link Frequency
foramen ovale 2
F8 (Mus musculus)
Pain Link Frequency Relevance Heat
epidural 1 94.04 High High
anesthesia 5 93.68 High High
cva 7 87.32 High High
Migraine 1 78.64 Quite High
Regional anesthesia 2 75.00 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Ultiva 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 10 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 1 100.00 Very High Very High Very High
Thrombosis Related Under Development 2 97.76 Very High Very High Very High
Stroke 7 96.00 Very High Very High Very High
Patent Foramen Ovale 5 95.08 Very High Very High Very High
Disease 4 93.00 High High
Hemorrhage 13 92.28 High High
Paradoxical Embolism 3 87.32 High High
Migraine With Aura 1 78.64 Quite High
Congenital Anomalies 1 52.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After consultation with the hematologist well ahead of the conception, appropriate laboratory workup including clotting factor levels including FVIII, vWF:RcoF, vWF:Ag on different occasions peripartum, and provision of adequate prophylactic medical treatment, she underwent Cesarean section under epidural anesthesia without neurological or bleeding complications. von Willebrand disease is the most common inherited bleeding disorder that may result in various bleeding complications in a parturient as a result of hemostatic challenges during pregnancy.
Negative_regulation (clotting) of Gene_expression (levels) of FVIII associated with coagulation disorder, anesthesia, epidural, hemorrhage and disease
1) Confidence 0.12 Published 2009 Journal J Ark Med Soc Section Abstract Doc Link 19475813 Disease Relevance 0.80 Pain Relevance 0.38
The magnitude of decrease of factor VIII at T1 was not different between the groups (decreased proportion of factor VIII at T1: non-O group 19.6 ± 21.3% vs.
Negative_regulation (decreased) of Gene_expression (proportion) of factor VIII
2) Confidence 0.11 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2876854 Disease Relevance 0 Pain Relevance 0
We assessed the occurrence of several prothrombotic states (factor V Leiden, prothrombin G20210A, deficiencies in protein S, protein C and antithrombin, lupus anticoagulant, anticardiolipin antibodies, elevated factor VIII, resistance to activated protein C) and classical risk factors for venous thrombosis in 57 adult patients with cryptogenic stroke and patent foramen ovale and in 104 matched controls.
Negative_regulation (deficiencies) of Gene_expression (resistance) of factor VIII in foramen ovale associated with patent foramen ovale, stroke, thrombosis related under development and systemic lupus erythematosus
3) Confidence 0.01 Published 2003 Journal Blood Coagul. Fibrinolysis Section Abstract Doc Link 12695749 Disease Relevance 1.32 Pain Relevance 0.16

General Comments

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