INT109913

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Context Info
Confidence 0.67
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAP3K14) nucleus (MAP3K14) cytoplasm (MAP3K14)
Anatomy Link Frequency
monocyte 1
MAP3K14 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 22 99.50 Very High Very High Very High
Inflammatory mediators 24 81.40 Quite High
cINOD 1 53.12 Quite High
dexamethasone 4 52.16 Quite High
Inflammation 111 50.00 Quite Low
cytokine 63 9.00 Low Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinal Diseases 1 95.56 Very High Very High Very High
INFLAMMATION 145 81.00 Quite High
Otitis Media 134 76.16 Quite High
Otitis Media With Effusion 92 51.20 Quite High
Bacterial Infection 4 15.96 Low Low
Stress 1 5.92 Low Low
Cholesteatoma 48 5.00 Very Low Very Low Very Low
Adhesions 14 5.00 Very Low Very Low Very Low
Infection 14 5.00 Very Low Very Low Very Low
Edema 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human RPE-monocyte co-culture induces chemokine gene expression through activation of MAPK and NIK cascade.
Positive_regulation (activation) of NIK in monocyte associated with chemokine
1) Confidence 0.67 Published 2003 Journal Exp. Eye Res. Section Title Doc Link 12697421 Disease Relevance 0.15 Pain Relevance 0.33
B-inducing kinase (NIK)-IKK-I?
Positive_regulation (inducing) of NIK
2) Confidence 0.02 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.36 Pain Relevance 0.04

General Comments

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