INT110184

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Context Info
Confidence 0.28
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 5.52
Pain Relevance 2.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuron 1
hippocampus 1
HMI (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 5 99.82 Very High Very High Very High
Angina 10 99.50 Very High Very High Very High
amygdala 7 96.62 Very High Very High Very High
Nucleus accumbens 64 94.72 High High
Dopamine 44 91.20 High High
corticosteroid 17 89.96 High High
Inflammation 102 89.48 High High
Nicotine 4 87.64 High High
Ventral tegmentum 2 84.56 Quite High
Central nervous system 18 81.12 Quite High
Disease Link Frequency Relevance Heat
Invasive Pulmonary Aspergillosis 174 100.00 Very High Very High Very High
Adhesions 3 100.00 Very High Very High Very High
Cv General 3 Under Development 7 99.50 Very High Very High Very High
Fungal Infection 23 98.96 Very High Very High Very High
Disease 81 98.20 Very High Very High Very High
Fever 13 96.48 Very High Very High Very High
Hematological Disease 6 95.88 Very High Very High Very High
Premature Birth 42 95.60 Very High Very High Very High
Endotoxemia 2 91.16 High High
Pneumonia 10 90.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If CS signaling is unaffected (and CS responses are even improved), and if US processing was unaffected in the bees selected for the experiments, how could IPA act on the association between CS and US in order to impair learning?
IPA Binding (association) of
1) Confidence 0.28 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2936933 Disease Relevance 0 Pain Relevance 0.08
Given the lack of diagnostic certainty, and mortality and morbidity rate associated with IPA, empirical initiation of antifungal has been recommended for neutropenic patients with fever who do not respond to broad-spectrum antibiotics [5,10,12].
IPA Binding (associated) of associated with fungal infection, fever and invasive pulmonary aspergillosis
2) Confidence 0.19 Published 2006 Journal Ann Clin Microbiol Antimicrob Section Body Doc Link PMC1550418 Disease Relevance 1.63 Pain Relevance 0.03
Among these patients, 2 had proven IPA, 3 had probable IPA, and 254 patients did not have IPA; the remaining 2 patients had possible IPA.
IPA Binding (had) of associated with invasive pulmonary aspergillosis
3) Confidence 0.07 Published 2010 Journal Annals of Saudi Medicine Section Body Doc Link PMC2886868 Disease Relevance 1.41 Pain Relevance 0.12
Some patients did not meet standard criteria for IPA, but had consistently high levels of Aspergillus DNA in BAL fluid by qPCR based on repeated assays (Table 3).
IPA Neg (not) Binding (criteria) of associated with invasive pulmonary aspergillosis
4) Confidence 0.06 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.36 Pain Relevance 0
In multivariate analysis, higher angina class was independently associated with lower IPA (P = 0.018).
IPA Binding (associated) of associated with angina
5) Confidence 0.05 Published 2003 Journal Catheter Cardiovasc Interv Section Abstract Doc Link 12720236 Disease Relevance 0.54 Pain Relevance 0.54
In order to reduce the complexity of the expected target display, we employed a commercially available engine for drug target identification and recording their interaction, Ingenuity Pathway Analysis (IPA) [23].
IPA Binding (interaction) of
6) Confidence 0.02 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923369 Disease Relevance 0.09 Pain Relevance 0.13
The IPA software was used to measure associations of these molecules with other molecules and disease functions stored in its knowledgebase.
IPA Binding (associations) of associated with disease
7) Confidence 0.02 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2714850 Disease Relevance 0.73 Pain Relevance 0
The basolateral amygdala (BLA) complex is critical for assigning motivational significant to discrete stimuli (Ito et al. 2006; Tye and Janak 2007; Tye et al. 2008), whereas the hippocampus is well-recognized for its role in contextual (Maren and Holt 2000) and spatial processing (Ito et al. 2006).
Ito Binding (recognized) of in hippocampus associated with hippocampus and amygdala
8) Confidence 0.02 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2770635 Disease Relevance 0 Pain Relevance 0.96
Moreover, the discovery that mast cells interact with the nervous system through synaptic cell adhesion molecules (Ito and Oonuma, 2006) has shed light into the complex neuron-immune reaction.
Ito Binding (interact) of in neuron associated with adhesions
9) Confidence 0.02 Published 2008 Journal Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine Section Body Doc Link PMC2990232 Disease Relevance 0.77 Pain Relevance 0.38

General Comments

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