INT110342

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Context Info
Confidence 0.33
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CNR1, TRPV1) cytosol (TRPV1) transport (TRPV1)
aging (CNR1) lipid metabolic process (TRPV1) response to stress (CNR1)
CNR1 (Homo sapiens)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 100.00 Very High Very High Very High
qutenza 6 99.56 Very High Very High Very High
Cannabinoid 3 75.00 Quite High
antagonist 1 72.36 Quite High
Spinal cord 1 46.96 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggest that in cells co-expressing both CB1 and VR1 receptors, pre-treatment with CB1 agonists inhibits or stimulates VR1 gating by capsaicin depending on whether or not cAMP-mediated signalling has been concomitantly activated.
CB1 Binding (pre-treatment) of VR1 associated with qutenza and agonist
1) Confidence 0.33 Published 2003 Journal Cell. Mol. Life Sci. Section Abstract Doc Link 12737320 Disease Relevance 0 Pain Relevance 0.63

General Comments

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