INT110347

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Context Info
Confidence 0.55
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Dpp4) extracellular region (Dpp4) cell adhesion (Dpp4)
Golgi apparatus (Dpp4) endoplasmic reticulum (Dpp4) plasma membrane (Dpp4)
Dpp4 (Mus musculus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 5 77.28 Quite High
Dynorphin 7 75.00 Quite High
Endogenous opioid 1 67.20 Quite High
Potency 1 55.36 Quite High
substance P 2 53.20 Quite High
Pain 3 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon activation with anti-CD3, up-regulation of both membrane CD26, as well as of DPPIV enzyme activity on R1.1 cells were observed.
Positive_regulation (up-regulation) of CD26
1) Confidence 0.55 Published 2003 Journal Life Sci. Section Abstract Doc Link 12738031 Disease Relevance 0 Pain Relevance 0.33
It exhibits a dipeptidyl-peptidase activity (DPP-IV) that cleaves the penultimate proline from the N-terminus of polypeptides, thereby regulating their activity and concentration.
Positive_regulation (exhibits) of DPP-IV
2) Confidence 0.47 Published 2006 Journal Behav. Brain Res. Section Abstract Doc Link 16154213 Disease Relevance 0.07 Pain Relevance 0

General Comments

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