INT110459

Context Info Confidence 0.32 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.31

nucleus (Atf2, Jun) DNA binding (Atf2, Jun) cytosol (Jun) intracellular (Atf2) transcription factor binding (Jun)

Atf2 (Mus musculus) Jun (Mus musculus)

Pain Link Frequency Relevance Heat Enkephalin 1 98.54 agonist 1 97.80 Delta opioid receptors 5 90.00 antagonist 1 79.68

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These studies determined whether a DOR agonist alone ([D-Ala(2)-D-Leu(5)]enkephalin; DADLE) affects phosphorylation of the activating transcription factor (ATF-2) and its interaction with the MAPK, c-Jun NH(2)-terminal kinase (JNK).

ATF-2 Binding (interaction) of c-Jun associated with agonist and enkephalin

1) Confidence 0.32 Published 2003 Journal Cell. Immunol. Section Abstract Doc Link 12747953 Disease Relevance 0 Pain Relevance 0.31

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