INT110485

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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tcf21)
Anatomy Link Frequency
spinal nerve 1
brain 1
Tcf21 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
lidocaine 9 99.12 Very High Very High Very High
Spinal nerve ligature 3 98.26 Very High Very High Very High
allodynia 6 97.56 Very High Very High Very High
withdrawal 3 80.56 Quite High
Neuropathic pain 1 76.44 Quite High
depression 1 55.52 Quite High
anticonvulsant 1 52.52 Quite High
ketamine 7 38.32 Quite Low
Pain 2 25.00 Low Low
neuralgia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 7 97.56 Very High Very High Very High
Stress 1 78.92 Quite High
Infection 1 78.48 Quite High
Nervous System Injury 1 77.72 Quite High
Depression 1 55.52 Quite High
Injury 10 50.72 Quite High
Stroke 12 50.00 Quite Low
Death 4 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we resolved the detailed time course of reversal of ipsilateral and contralateral allodynia in rats with spinal nerve ligation by a single systemic infusion of lidocaine, to 4 microg/ml, given either 2 days after ligation (POD2) or 7 days after ligation (POD7).
POD2 Binding (ligation) of in spinal nerve associated with allodynia, spinal nerve ligature and lidocaine
1) Confidence 0.36 Published 2003 Journal Pain Section Abstract Doc Link 12749955 Disease Relevance 0.49 Pain Relevance 1.32
On the other hand, cathodal stimulation for 2 weeks was associated with deterioration at POD 16, which is probably attributable to a cumulative effect caused by decreased excitability of the infarcted brain.
POD 16 Binding (deterioration) of in brain
2) Confidence 0.08 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2946662 Disease Relevance 0.26 Pain Relevance 0.05

General Comments

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