INT110491

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Context Info
Confidence 0.34
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.83
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cnr2) plasma membrane (Cnr2) signal transducer activity (Cnr2)
Cnr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Antihyperalgesic 2 99.26 Very High Very High Very High
antagonist 2 99.16 Very High Very High Very High
Cancer pain 2 98.70 Very High Very High Very High
Inflammation 4 96.36 Very High Very High Very High
Hyperalgesia 10 95.56 Very High Very High Very High
Cannabinoid 7 82.56 Quite High
Pain 5 75.00 Quite High
Deep tissue 4 75.00 Quite High
agonist 2 75.00 Quite High
Cannabinoid receptor 1 63.40 Quite High
Disease Link Frequency Relevance Heat
Cancer Pain 2 98.70 Very High Very High Very High
INFLAMMATION 4 96.36 Very High Very High Very High
Hyperalgesia 10 95.56 Very High Very High Very High
Cancer 5 87.84 High High
Catalepsy 1 87.68 High High
Myalgia 2 75.00 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the cancer pain model, the antihyperalgesic effect of WIN55,212-2 was partially blocked by pretreatment with the selective CB1 (SR141716A) but not the CB2 (SR144528) receptor antagonist.
Negative_regulation (blocked) of CB2 Binding (pretreatment) of associated with antihyperalgesic, cancer pain and antagonist
1) Confidence 0.34 Published 2003 Journal Pain Section Abstract Doc Link 12749972 Disease Relevance 1.83 Pain Relevance 1.82

General Comments

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