INT110495

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Context Info
Confidence 0.70
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 7
Disease Relevance 3.14
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Galp)
Anatomy Link Frequency
posterior pituitary 2
Galp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 21 100.00 Very High Very High Very High
Inflammation 14 99.22 Very High Very High Very High
Arthritis 14 97.04 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 14 99.40 Very High Very High Very High
INFLAMMATION 14 99.22 Very High Very High Very High
Shock 7 97.80 Very High Very High Very High
Experimental Arthritis 14 97.40 Very High Very High Very High
Nociception 7 91.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggested that inflammatory stresses may be a potent stimulant to induce the expression of the GALP gene in the PP.
Positive_regulation (induce) of Gene_expression (expression) of GALP gene associated with stress and inflammation
1) Confidence 0.70 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.56 Pain Relevance 0.17
Intraperitoneal (i.p.) injection of lipopolysaccharide (LPS) also caused a marked increase of GALP gene expression in the PP.
Positive_regulation (caused) of Gene_expression (expression) of GALP gene
2) Confidence 0.70 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.41 Pain Relevance 0.15
Subcutaneous (s.c.) injection of 5% formalin in the bilateral hind paws caused a moderate increase of GALP gene expression in the PP.
Positive_regulation (caused) of Gene_expression (expression) of GALP gene
3) Confidence 0.70 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.43 Pain Relevance 0.15
Induction of galanin-like peptide gene expression in the rat posterior pituitary gland during endotoxin shock and adjuvant arthritis.
Positive_regulation (Induction) of Gene_expression (expression) of galanin-like peptide in posterior pituitary associated with pain, shock, experimental arthritis and arthritis
4) Confidence 0.47 Published 2003 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 12750014 Disease Relevance 0.43 Pain Relevance 0.39
Subcutaneous (s.c.) injection of 5% formalin in the bilateral hind paws caused a moderate increase of GALP gene expression in the PP.
Positive_regulation (increase) of Gene_expression (expression) of GALP gene
5) Confidence 0.47 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.43 Pain Relevance 0.15
The levels of GALP mRNA in the PP were markedly increased by two peaks at 24 h and 15 days after s.c. injection of heat-inactivated M. butyricum that induced adjuvant arthritis.
Positive_regulation (increased) of Gene_expression (levels) of GALP mRNA associated with experimental arthritis and arthritis
6) Confidence 0.47 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.48 Pain Relevance 0.17
Intraperitoneal (i.p.) injection of lipopolysaccharide (LPS) also caused a marked increase of GALP gene expression in the PP.
Positive_regulation (increase) of Gene_expression (expression) of GALP gene
7) Confidence 0.47 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12750014 Disease Relevance 0.41 Pain Relevance 0.15

General Comments

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