INT110611

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Context Info
Confidence 0.39
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (KCNK10) transport (KCNK10) plasma membrane (KCNK10)
Anatomy Link Frequency
myometrium 1
neurons 1
KCNK10 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 29 100.00 Very High Very High Very High
agonist 1 29.12 Quite Low
Regional anesthesia 1 25.00 Low Low
antagonist 3 22.36 Low Low
ischemia 3 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-term Labor 5 72.12 Quite High
Acidosis 2 52.64 Quite High
Premature Birth 3 19.52 Low Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 2 5.00 Very Low Very Low Very Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low
Dysmenorrhea 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Fetal Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although claimed to be absent in murine myometrium [18], we have described the expression of the potassium channels, subfamily K, member 4 (KCNK4) a two-pore potassium channel (K2P4.1) known as TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) and member 2 (KCNK2) a two-pore potassium channel (K2P2.1) known as TREK-1 (TWIK-related K+ channel) in human myometrium [19] as did Bai et al. in the same year [20].
Gene_expression (expression) of TWIK-related in myometrium associated with potassium channel
1) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928262 Disease Relevance 0.14 Pain Relevance 0.37
Human TWIK-related K(+) channels (TREK-1) stabilize the membrane potential (mp) of neurons and have a major role in the regulation of membrane excitability.
Gene_expression (stabilize) of TWIK-related K in neurons
2) Confidence 0.16 Published 2003 Journal Anesth. Analg. Section Abstract Doc Link 12760993 Disease Relevance 0.05 Pain Relevance 0

General Comments

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