INT110749

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Context Info
Confidence 0.34
First Reported 2003
Last Reported 2010
Negated 0
Speculated 2
Reported most in Abstract
Documents 9
Total Number 11
Disease Relevance 0.51
Pain Relevance 1.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (Ppt1) extracellular space (Ppt1) cofactor metabolic process (Ppt1)
extracellular region (Ppt1) Golgi apparatus (Ppt1) nucleus (Ppt1)
Anatomy Link Frequency
uterus 3
granulosa cells 2
Mouse 1
Ppt1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 18 100.00 Very High Very High Very High
agonist 10 99.68 Very High Very High Very High
lumbar region 42 95.60 Very High Very High Very High
anesthesia 1 91.72 High High
Pain 123 88.72 High High
Pain threshold 3 77.88 Quite High
qutenza 14 71.92 Quite High
antagonist 7 60.56 Quite High
Hyperalgesia 6 5.00 Very Low Very Low Very Low
backache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 123 88.72 High High
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Handedness 3 5.00 Very Low Very Low Very Low
Neck Pain 3 5.00 Very Low Very Low Very Low
Low Back Pain 3 5.00 Very Low Very Low Very Low
Osteoporosis 3 5.00 Very Low Very Low Very Low
Shoulder Pain 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Hypogonadotropic Hypogonadism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mouse oocytes expressed PPT-A and -B mRNA transcripts.
Gene_expression (expressed) of PPT in Mouse
1) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.13
The preprotachykinin (PPT) genes, PPT-A, PPT-B and PPT-C, that encode substance P/neurokinin A, neurokinin B, and hemokinin-1, respectively, and the genes that encode the tachykinin NK1, NK2, and NK3 receptors were all expressed, at different levels, in the uterus of superovulated, unfertilized mice.
Gene_expression (expressed) of PPT in uterus associated with substance p
2) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.05
Isolated cumulus granulosa cells expressed PPT-A, PPT-B, PPT-C, and NEP and low levels of the tachykinin NK1 and NK2 receptors.
Gene_expression (expressed) of PPT in granulosa cells
3) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.10
The preprotachykinin (PPT) genes, PPT-A, PPT-B and PPT-C, that encode substance P/neurokinin A, neurokinin B, and hemokinin-1, respectively, and the genes that encode the tachykinin NK1, NK2, and NK3 receptors were all expressed, at different levels, in the uterus of superovulated, unfertilized mice.
Gene_expression (expressed) of PPT in uterus associated with substance p
4) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.05
The preprotachykinin (PPT) genes, PPT-A, PPT-B and PPT-C, that encode substance P/neurokinin A, neurokinin B, and hemokinin-1, respectively, and the genes that encode the tachykinin NK1, NK2, and NK3 receptors were all expressed, at different levels, in the uterus of superovulated, unfertilized mice.
Gene_expression (expressed) of PPT in uterus associated with substance p
5) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.05
Isolated cumulus granulosa cells expressed PPT-A, PPT-B, PPT-C, and NEP and low levels of the tachykinin NK1 and NK2 receptors.
Gene_expression (expressed) of PPT in granulosa cells
6) Confidence 0.34 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.10
A low expression of the three tachykinin receptors was observed but PPT-C and NEP were undetectable.
Gene_expression (undetectable) of PPT
7) Confidence 0.30 Published 2003 Journal Biol. Reprod. Section Abstract Doc Link 12773411 Disease Relevance 0 Pain Relevance 0.14
agonist propylpyrazole triol (PPT, Tocris, Ellisville, MO, 75 ?
Gene_expression (triol) of PPT associated with agonist
8) Confidence 0.22 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2724541 Disease Relevance 0 Pain Relevance 0.24
The mean value of the two measurements with the lowest variance was used as the PPT value of this point.
Gene_expression (value) of PPT
9) Confidence 0.20 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2964538 Disease Relevance 0.23 Pain Relevance 0.25
Both absolute PPT values and normalized PPT values were analyzed.
Spec (analyzed) Gene_expression (values) of PPT
10) Confidence 0.20 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2964538 Disease Relevance 0.14 Pain Relevance 0.19
Both absolute PPT values and normalized PPT values were analyzed.
Spec (analyzed) Gene_expression (values) of PPT
11) Confidence 0.20 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2964538 Disease Relevance 0.14 Pain Relevance 0.19

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