INT110764

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Context Info
Confidence 0.09
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tbt1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 3 91.04 High High
Pain 2 25.00 Low Low
Eae 5 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 95 97.68 Very High Very High Very High
Disease 27 86.40 High High
Apoptosis 24 81.32 Quite High
Muscle Disease 10 50.00 Quite Low
Death 1 45.36 Quite Low
Muscle Weakness 17 5.00 Very Low Very Low Very Low
Convulsion 13 5.00 Very Low Very Low Very Low
Bone Disease 12 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 8 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The fact that the use of TBT in antifouling paints was banned in 1991 for small boats within the European Community seems not to have resulted in a decrease of TBT levels in marine biota.
Negative_regulation (decrease) of TBT
1) Confidence 0.09 Published 2003 Journal Environ. Sci. Technol. Section Abstract Doc Link 12775042 Disease Relevance 0 Pain Relevance 0
The Bone Surface area/Bone Volume (BS/BV), Trabecular Space (Tb.Sp) was not different, but significantly decreased Trabecular Pattern Factor (Tb.P.F) and increased Cortical wall Thickness (C.Th) in knock-in mice was observed compared to WT mice (Table 2).
Negative_regulation (decreased) of Trabecular Pattern Factor associated with targeted disruption
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 1.08 Pain Relevance 0.05

General Comments

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