INT110795

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Context Info
Confidence 0.26
First Reported 2003
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.65
Pain Relevance 2.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cacna1a) DNA binding (Cacna1a) transmembrane transport (Cacna1a)
cytoplasm (Cacna1a) cell death (Cacna1a) nucleus (Cacna1a)
Anatomy Link Frequency
adrenal medulla 2
Cacna1a (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 126 100.00 Very High Very High Very High
long-term potentiation 74 100.00 Very High Very High Very High
isoflurane 11 100.00 Very High Very High Very High
qutenza 79 98.86 Very High Very High Very High
medulla 3 96.88 Very High Very High Very High
anesthesia 8 96.44 Very High Very High Very High
Hippocampus 6 93.20 High High
antagonist 18 88.00 High High
Opioid 3 87.28 High High
narcan 1 77.08 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 8 88.64 High High
Targeted Disruption 3 88.28 High High
Decapitation 1 74.40 Quite High
Nociception 2 47.68 Quite Low
Anxiety Disorder 7 30.16 Quite Low
Pain 5 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Investigations of the signal pathways further supported that activation of alpha 1A -adrenoceptor is responsible for the stimulatory effect of caffeic acid on BER secretion from the adrenal medulla.
Regulation (responsible) of Positive_regulation (activation) of alpha 1A in adrenal medulla associated with medulla
1) Confidence 0.26 Published 2003 Journal Horm. Metab. Res. Section Abstract Doc Link 12778369 Disease Relevance 0.58 Pain Relevance 0.39
As shown in Fig. 7A, capsaicin caused a significant enhancement of the magnitude of EC-induced LA-LTP in the isoflurane group (control: 128.1±4.1% [n?
Regulation (control) of Positive_regulation (induced) of LA associated with qutenza, isoflurane, long-term potentiation and amygdala
2) Confidence 0.04 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020947 Disease Relevance 0.07 Pain Relevance 1.68

General Comments

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