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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

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extracellular region (REG1A, CTSB) peptidase activity (CTSB) mitochondrion (CTSB)
extracellular space (CTSB) intracellular (CTSB) lysosome (CTSB)
Anatomy Link Frequency
cleavage 2
REG1A (Homo sapiens)
CTSB (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 2 81.20 Quite High
Nicotine 1 42.52 Quite Low
Enkephalin 1 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it is notable that production of catestatin itself (CgA(344)(-)(364)) utilizes more unusual cleavage sites at the NH(2)-terminal sides of downward arrow R and downward arrow RR basic residue sites, consistent with the cleavage specificities of the chromaffin granule cysteine protease "PTP" that participates in proenkephalin processing.
PTP Positive_regulation (participates) of Gene_expression (production) of chromaffin granule cysteine protease in cleavage
1) Confidence 0.01 Published 2003 Journal Biochemistry Section Abstract Doc Link 12795588 Disease Relevance 0 Pain Relevance 0.04

General Comments

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