INT111080

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Context Info
Confidence 0.02
First Reported 2002
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (CA1, CA2) cytoplasm (CA1, CA2) cytosol (CA2)
extracellular space (CA2) Golgi apparatus (CA1) response to stress (CA2)
Anatomy Link Frequency
red blood cells 1
CA1 (Homo sapiens)
CA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 12 99.84 Very High Very High Very High
beta blocker 4 68.20 Quite High
rheumatoid arthritis 1 51.92 Quite High
antagonist 5 13.12 Low Low
agonist 2 5.00 Very Low Very Low Very Low
eye pain 1 5.00 Very Low Very Low Very Low
topical agent 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 13 99.84 Very High Very High Very High
Autoimmune Disease 3 81.20 Quite High
Ocular Hypertension 110 71.40 Quite High
Hypergammaglobulinemia 1 71.04 Quite High
Increased Venous Pressure Under Development 1 67.12 Quite High
Acid Base Imbalance 1 65.44 Quite High
Glaucoma 38 65.20 Quite High
Low Tension Glaucoma 3 59.36 Quite High
Rheumatoid Arthritis 1 51.92 Quite High
Systemic Lupus Erythematosus 1 47.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Metabolism of dorzolamide produces N-desthyl which also binds to red blood cells to inhibit carbonic anhydrase I to a greater extent than carbonic anhydrase II.
anhydrase I Neg (inhibit) Binding (inhibit) of carbonic anhydrase II in red blood cells
1) Confidence 0.02 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693974 Disease Relevance 0.53 Pain Relevance 0.03
The aim of the present study was to evaluate the presence of serum Abs to CA-I and CA-II in CP and the relative affinity of these Abs.
CA-I Binding (presence) of CA-II associated with chronic pancreatitis
2) Confidence 0.00 Published 2002 Journal ScientificWorldJournal Section Abstract Doc Link 12806141 Disease Relevance 1.09 Pain Relevance 0.69

General Comments

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