INT111139

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.40
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Tp53) mitochondrion (Tp53) aging (Tp53)
endoplasmic reticulum (Tp53) enzyme binding (Tp53) protein complex assembly (Tp53)
Anatomy Link Frequency
neurons 2
B-cell 1
Tp53 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
abdominal pain 1 87.04 High High
withdrawal 6 50.00 Quite Low
GABAergic 6 40.16 Quite Low
fibrosis 14 25.92 Quite Low
Nerve growth factor 88 5.00 Very Low Very Low Very Low
Hippocampus 14 5.00 Very Low Very Low Very Low
Intracerebroventricular 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 1 98.54 Very High Very High Very High
Myocardial Infarction 78 98.44 Very High Very High Very High
Death 25 97.52 Very High Very High Very High
Epstein-barr Virus 1 94.84 High High
Lymphoproliferative Disease 2 91.72 High High
Abdominal Pain 1 87.04 High High
Splenomegaly 1 86.40 High High
Apoptosis 62 70.56 Quite High
Diabetes Mellitus 55 68.76 Quite High
Targeted Disruption 8 49.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We examined myocardial Sirt1-, acetyl-p53- and p53 protein expression by western blotting and Sirt1-localization by immunohistochemistry.
Localization (localization) of p53
1) Confidence 0.45 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.50 Pain Relevance 0
In these conditions, cleaved caspase-3 and p53 clearly labeled damaged neurons as indicated by their co-localization with altered Neurotrace labeling (Additional file 1).
Localization (localization) of p53 in neurons
2) Confidence 0.28 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2826326 Disease Relevance 0.22 Pain Relevance 0
In these conditions, cleaved caspase-3 and p53 clearly labeled damaged neurons as indicated by their co-localization with altered Neurotrace labeling (Additional file 1).
Localization (cleaved) of p53 in neurons
3) Confidence 0.28 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2826326 Disease Relevance 0.22 Pain Relevance 0
An indolent B-cell lymphoma with t(2;8)(p12;q24) abnormality and absence of C-MYC amplification and TP53 deletion.
Localization (deletion) of TP53 in B-cell associated with lymphatic system cancer
4) Confidence 0.07 Published 2003 Journal Cancer Genet. Cytogenet. Section Title Doc Link 12810261 Disease Relevance 0.46 Pain Relevance 0.09

General Comments

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