INT111162

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.78
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (EFNA1) plasma membrane (EFNA1) cell-cell signaling (EFNA1)
EFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 13 100.00 Very High Very High Very High
Inflammation 5 99.30 Very High Very High Very High
cytokine 3 97.48 Very High Very High Very High
antagonist 1 96.12 Very High Very High Very High
Migraine 11 85.36 High High
Calcitonin gene-related peptide 1 80.16 Quite High
Neuropeptide 1 75.68 Quite High
Bile 1 75.68 Quite High
depression 1 73.08 Quite High
headache 1 65.84 Quite High
Disease Link Frequency Relevance Heat
Endometriosis (extended) 13 100.00 Very High Very High Very High
INFLAMMATION 4 99.30 Very High Very High Very High
Disease 3 96.04 Very High Very High Very High
Increased Venous Pressure Under Development 3 96.00 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

1 95.20 Very High Very High Very High
Insulin Resistance 1 94.60 High High
Obesity 2 91.88 High High
Headache 12 85.36 High High
Necrosis 1 82.00 Quite High
Cancer 1 81.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Group 1 target genes are up-regulated during the normal window of implantation but significantly decreased in women with endometriosis: IL-15, proline-rich protein, B61, Dickkopf-1, glycodelin, N-acetylglucosamine-6-O-sulfotransferase, G0S2 protein, and purine nucleoside phosphorylase.
Negative_regulation (decreased) of B61 associated with endometriosis
1) Confidence 0.03 Published 2003 Journal Endocrinology Section Abstract Doc Link 12810542 Disease Relevance 0.78 Pain Relevance 0.27
The anti-inflammatory activities of adiponectin include inhibition of IL-6 and TNF-induced IL-8 formation, as well as induction of the anti-inflammatory cytokines IL-10 and IL-1 receptor antagonist.
Negative_regulation (inhibition) of TNF-induced associated with inflammation, antagonist and cytokine
2) Confidence 0.00 Published 2007 Journal Cephalalgia Section Abstract Doc Link 17448181 Disease Relevance 1.90 Pain Relevance 1.17

General Comments

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