INT111199

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Context Info
Confidence 0.16
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 18
Disease Relevance 5.65
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acly) nucleolus (Acly) plasma membrane (Acly)
nucleus (Acly) ligase activity (Acly) lipid metabolic process (Acly)
Anatomy Link Frequency
tendon 4
Fat 2
extremity 2
tears 1
medial 1
Acly (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 2 99.74 Very High Very High Very High
anesthesia 8 98.52 Very High Very High Very High
Osteoarthritis 18 97.64 Very High Very High Very High
Pain 14 92.56 High High
imagery 3 90.00 High High
ischemia 3 87.00 High High
Restless leg syndrome 1 86.16 High High
cytokine 47 85.32 High High
cva 9 48.88 Quite Low
metalloproteinase 59 10.72 Low Low
Disease Link Frequency Relevance Heat
Injury 278 100.00 Very High Very High Very High
Osteoarthritis 15 97.64 Very High Very High Very High
Hyperlipidemia 2 97.60 Very High Very High Very High
Rotator Cuff Tears 24 97.44 Very High Very High Very High
Thrombosis Related Under Development 18 96.80 Very High Very High Very High
Diabetes Mellitus 1 96.56 Very High Very High Very High
Nicotine Addiction 1 95.80 Very High Very High Very High
Hypertension 3 95.44 Very High Very High Very High
Rupture 36 95.12 Very High Very High Very High
Hematoma 9 94.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, ACL reconstruction, which requires a tendon graft to be put inside a bone tunnel, has failure rate ranged 10%-25%, depending on the evaluation criteria used[18].
Gene_expression (reconstruction) of ACL in tendon
1) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.25 Pain Relevance 0
The ACL is then excised after medial parapatellar arthrotomy.
Gene_expression (excised) of ACL in medial
2) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.05 Pain Relevance 0.10
3.1 ACL reconstruction
Gene_expression (reconstruction) of ACL
3) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.38 Pain Relevance 0
The histological scoring system allows the comparison of outcomes of different interventional studies and facilitates the interpretation of results of biomechanical test in outcome studies.

4.1.4 Local bone loss after ACL reconstruction

Gene_expression (reconstruction) of ACL
4) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.07 Pain Relevance 0
2.1 ACL reconstruction
Gene_expression (reconstruction) of ACL
5) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.45 Pain Relevance 0.09
Can we completely replace the tendon graft inside the bone tunnel by bone and recreate the normal tendon-bone insertion at the intraarticualr tunnel exit in ACL reconstruction?
Gene_expression (reconstruction) of ACL in tendon
6) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0 Pain Relevance 0
As ACL has poor healing capacity, reconstruction of ACL with tendon graft is commonly performed.
Gene_expression (reconstruction) of ACL in tendon
7) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.35 Pain Relevance 0.06
With the growing popularity of using the hamstring graft for ACL reconstruction, studies on the biology and treatment options for improvement of tendon graft to bone tunnel healing have become the focus of research in ACL reconstruction.

2.2 PPT repair

Gene_expression (reconstruction) of ACL in hamstring
8) Confidence 0.16 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.42 Pain Relevance 0
In particular, the association between lower extremity muscular strength and hop test results in individuals with ACL injury or ACL reconstruction has previously been found to be low to moderate [27].
Gene_expression (reconstruction) of ACL in extremity associated with injury
9) Confidence 0.15 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2908077 Disease Relevance 0.10 Pain Relevance 0
The two ACL-injured cohorts included subjects who had and who had not undergone surgical ACL reconstruction, as well as subjects in a well rehabilitated stage.
Gene_expression (reconstruction) of ACL
10) Confidence 0.15 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2908077 Disease Relevance 0.17 Pain Relevance 0
In particular, the association between lower extremity muscular strength and hop test results in individuals with ACL injury or ACL reconstruction has previously been found to be low to moderate [27].
Gene_expression (reconstruction) of ACL in extremity associated with injury
11) Confidence 0.15 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2908077 Disease Relevance 0.10 Pain Relevance 0
Differential expression of fatty acid synthase genes, Acl, Fat and Kas, in Capsicum fruit.
Gene_expression (expression) of Acl in Fat associated with qutenza
12) Confidence 0.11 Published 2003 Journal J. Exp. Bot. Section Title Doc Link 12810854 Disease Relevance 0 Pain Relevance 0.10
Three candidate genes for subunits in this complex, Kas, Acl, and Fat, isolated based on differential expression, were characterized.
Gene_expression (expression) of Acl in Fat
13) Confidence 0.10 Published 2003 Journal J. Exp. Bot. Section Abstract Doc Link 12810854 Disease Relevance 0 Pain Relevance 0
In spite of significant efforts being made to improve the surgical procedures for ACL reconstruction during the last twenty years, many patients still develop osteoarthritis early in the long term[13,14].
Gene_expression (reconstruction) of ACL associated with osteoarthritis
14) Confidence 0.09 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2879239 Disease Relevance 0.47 Pain Relevance 0.08
For patients over 40 years of age that have proximal ACL tears, this procedure has successful results[88].
Gene_expression (tears) of ACL in tears
15) Confidence 0.09 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2879239 Disease Relevance 0.40 Pain Relevance 0.09
We have applied the SIS bioscaffold to treat a central third defect of patellar tendon in a rabbit model, which is commonly the donor site of autografts for ACL reconstruction.
Gene_expression (reconstruction) of ACL in tendon
16) Confidence 0.09 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2879239 Disease Relevance 0.08 Pain Relevance 0.04
IgG/IgM/IgA aCL and anti-beta2-gpI were detected by enzyme-linked immunoabsorbant assays (ELISA).
Gene_expression (detected) of aCL
17) Confidence 0.03 Published 2007 Journal Angiology Section Abstract Doc Link 17626983 Disease Relevance 1.39 Pain Relevance 0.17
The presence of IgM or IgG anticardiolipin (aCL) antibodies, IgG anti-beta-2-glycoprotein1 (anti-?
Gene_expression (presence) of aCL
18) Confidence 0.02 Published 2006 Journal J Autoimmune Dis Section Body Doc Link PMC1448177 Disease Relevance 0.97 Pain Relevance 0.04

General Comments

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