INT111285

Context Info Confidence 0.50 First Reported 2003 Last Reported 2003 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.12

extracellular space (AGRP) extracellular region (AGRP) Golgi apparatus (AGRP) plasma membrane (MC4R) signal transducer activity (MC4R)

AGRP (Homo sapiens) MC4R (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 1 91.60 melanocortin 1 receptor 1 77.84

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our previous studies have suggested that in addition to exoloops 2 and 3, several transmembrane domains of MC4R may be important for AGRP binding.

Spec (may) Positive_regulation (important) of AGRP Binding (binding) of MC4R

1) Confidence 0.50 Published 2003 Journal Mol. Pharmacol. Section Abstract Doc Link 12815165 Disease Relevance 0 Pain Relevance 0.12

General Comments

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