INT11138

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Context Info
Confidence 0.56
First Reported 1992
Last Reported 2006
Negated 2
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.80
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifng) extracellular region (Ifng)
Ifng (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 93.32 High High
antidepressant 3 76.44 Quite High
alcohol 1 76.40 Quite High
Neuritis 5 75.00 Quite High
Inflammation 4 75.00 Quite High
Paracetamol 1 74.72 Quite High
monoamine 2 61.28 Quite High
Serotonin 1 57.36 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 5 92.92 High High
Experimental Autoimmune Neuritis 5 75.00 Quite High
Hepatotoxicity 1 72.68 Quite High
Syndrome 1 65.60 Quite High
Autoimmune Disease 1 5.00 Very Low Very Low Very Low
Mental Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the IFN-gamma secretion assay zimeldine, CPP 200, clomipramine and maprotiline all in a concentration-dependent mode reduced the number of IFN-gamma secreting cells while norzimeldine and imipramine did not affect the IFN-gamma secretion.
Neg (not) Regulation (ffect ) of Localization (ecretion.) of IFN-gamma
1) Confidence 0.56 Published 1992 Journal J. Neuroimmunol. Section Abstract Doc Link 1535634 Disease Relevance 0.40 Pain Relevance 0.49
APAP by itself did not alter release of TNF-alpha, PGE(2), IL-10, Gro/KC or IFN-gamma; however, in the presence of LPS, APAP enhanced LPS-induced TNF-alpha and Gro/KC release.
Neg (not) Regulation (alter) of Localization (release) of IFN-gamma
2) Confidence 0.23 Published 2006 Journal Toxicol In Vitro Section Abstract Doc Link 16782301 Disease Relevance 0.39 Pain Relevance 0.27

General Comments

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