INT111406

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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2ry1) aging (P2ry1) plasma membrane (P2ry1)
signal transducer activity (P2ry1)
Anatomy Link Frequency
sensory neurons 1
platelets 1
P2ry1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 2 99.18 Very High Very High Very High
Kinase C 3 98.12 Very High Very High Very High
adenocard 3 85.84 High High
agonist 1 82.72 Quite High
aspirin 43 81.48 Quite High
antagonist 6 70.16 Quite High
Calcitonin gene-related peptide 1 67.64 Quite High
substance P 1 66.24 Quite High
Neuropeptide 1 57.52 Quite High
cINOD 1 31.12 Quite Low
Disease Link Frequency Relevance Heat
Disease 3 89.04 High High
Stroke 4 84.56 Quite High
Myocardial Infarction 8 66.60 Quite High
INFLAMMATION 3 30.88 Quite Low
Cv General 3 Under Development 4 22.08 Low Low
Diabetes Mellitus 3 21.32 Low Low
Thrombosis 10 11.44 Low Low
Atherosclerosis 7 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Acute Coronary Syndrome 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreating sensory neurons with bisindolylmaleimide I, a selective protein kinase C (PKC) inhibitor, attenuates the augmentation of capsaicin-induced peptide release by ATP, further implicating P2Y receptors in the actions of ATP.
P2Y Binding (implicating) of in sensory neurons associated with kinase c and qutenza
1) Confidence 0.36 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12829729 Disease Relevance 0 Pain Relevance 0.49
ADP activates platelets by binding its purinergic P2Y1 and P2Y12 receptors.
P2Y1 Binding (binding) of in platelets
2) Confidence 0.05 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515423 Disease Relevance 0.31 Pain Relevance 0.21

General Comments

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