INT111504

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ptprg) extracellular region (Pnoc)
Anatomy Link Frequency
brain 2
Pnoc (Rattus norvegicus)
Ptprg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 4 100.00 Very High Very High Very High
agonist 2 98.68 Very High Very High Very High
Endogenous opioid 2 97.52 Very High Very High Very High
Analgesic 4 80.88 Quite High
Opioid 2 76.56 Quite High
opioid receptor 4 75.00 Quite High
narcan 4 59.52 Quite High
mu opioid receptor 8 49.76 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Utilizing agonist-stimulated GTPgammaS autoradiography, we analyzed the ability of preproorphanin FQ (ppOFQ) peptides to stimulate [35S]-GTPgammaS binding in adult rat brain.
preproorphanin FQ Positive_regulation (stimulate) of GTPgammaS Spec (analyzed) Binding (binding) of in brain associated with agonist
1) Confidence 0.01 Published 2003 Journal J. Chem. Neuroanat. Section Abstract Doc Link 12842269 Disease Relevance 0 Pain Relevance 0.47
Orphanin FQ (OFQ) stimulated [35S]-GTPgammaS binding in a pattern similar to that described for [125I]-OFQ at the endogenous opioid receptor-like (ORL1) receptor.
Orphanin FQ Positive_regulation (stimulated) of GTPgammaS Binding (binding) of associated with orphanin and endogenous opioid
2) Confidence 0.01 Published 2003 Journal J. Chem. Neuroanat. Section Abstract Doc Link 12842269 Disease Relevance 0 Pain Relevance 0.50

General Comments

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