INT11155

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Context Info
Confidence 0.34
First Reported 1991
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.95
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TGFA) extracellular space (TGFA) extracellular region (TGFA)
plasma membrane (TGFA) nucleus (TGFA)
Anatomy Link Frequency
pancreas 1
TGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 85.36 High High
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 99.30 Very High Very High Very High
Adenocarcinoma 1 97.72 Very High Very High Very High
Pancreatic Cancer 6 96.96 Very High Very High Very High
Pancreatitis 4 85.36 High High
Cancer 2 64.72 Quite High
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is in vitro evidence that simultaneous overproduction of one of its ligands, transforming growth factor alpha (TGF-alpha), might result in an autocrine loop with an increased proliferation signal.
transforming growth factor alpha Binding (ligands) of
1) Confidence 0.34 Published 1991 Journal J. Pathol. Section Abstract Doc Link 1707959 Disease Relevance 0.53 Pain Relevance 0.15
Abnormalities in expression of two of the known ligands of the EGFR, transforming growth factor alpha and epidermal growth factor, occur frequently in ductal adenocarcinoma of the human pancreas.
transforming growth factor alpha Binding (ligands) of in pancreas associated with adenocarcinoma and congenital anomalies
2) Confidence 0.23 Published 1992 Journal J. Pathol. Section Abstract Doc Link 1538276 Disease Relevance 0.42 Pain Relevance 0.07

General Comments

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