INT111575

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Context Info
Confidence 0.78
First Reported 2003
Last Reported 2010
Negated 0
Speculated 2
Reported most in Abstract
Documents 15
Total Number 19
Disease Relevance 7.97
Pain Relevance 1.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Muc5ac) molecular_function (Muc5ac)
Anatomy Link Frequency
stomach 3
neck 2
appendix 2
glands 1
Muc5ac (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 11 95.72 Very High Very High Very High
alcohol 8 94.84 High High
mu opioid receptor 2 92.40 High High
Chronic pancreatitis 3 82.88 Quite High
imagery 4 81.84 Quite High
opioid receptor 1 80.24 Quite High
Serotonin 10 76.76 Quite High
cytokine 3 76.52 Quite High
Inflammation 12 76.12 Quite High
Opioid 3 75.84 Quite High
Disease Link Frequency Relevance Heat
Ulcers 120 99.98 Very High Very High Very High
Cancer 271 99.88 Very High Very High Very High
Pancreatic Cancer 3 99.28 Very High Very High Very High
Metastasis 83 99.16 Very High Very High Very High
Malignant Neoplastic Disease 25 98.08 Very High Very High Very High
Ductal Carcinoma 3 96.44 Very High Very High Very High
INFLAMMATION 23 95.48 Very High Very High Very High
Pseudomyxoma Peritonei 4 93.76 High High
Metaplasia 111 93.36 High High
Carcinoid 330 88.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, little is known about expression of the MUC5AC gene.
Gene_expression (expression) of MUC5AC gene
1) Confidence 0.78 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.10 Pain Relevance 0.14
The injection of hydrocortisone induced PgC mRNA expression in the infant rat stomach, whereas MUC5AC and PgF mRNA expression decreased.
Gene_expression (expression) of MUC5AC in stomach
2) Confidence 0.78 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.07 Pain Relevance 0.10
We examined developmental changes in rat MUC5AC mRNA expression and the effect of glucocorticoid on MUC5AC mRNA expression in infant rat gastric mucosa.
Gene_expression (expression) of MUC5AC
3) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.09 Pain Relevance 0.13
We examined developmental changes in rat MUC5AC mRNA expression and the effect of glucocorticoid on MUC5AC mRNA expression in infant rat gastric mucosa.
Gene_expression (expression) of MUC5AC
4) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.09 Pain Relevance 0.14
These results suggest that developmental changes of MUC5AC mRNA expression differ from those of Pgs, and are not induced by glucocorticoid.
Gene_expression (expression) of MUC5AC
5) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.06 Pain Relevance 0.09
The expression of MUC5AC mRNA increased from 10 d of age, which was about one week earlier than that of PgC mRNA.
Gene_expression (expression) of MUC5AC
6) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.08 Pain Relevance 0.12
Expression levels of MUC5AC mRNA in the stomach of 0 to 30-d-old and 8-week-old (adult) rats were evaluated by reverse transcription polymerase chain reaction (RT-PCR) and by in situ hybridization.
Gene_expression (Expression) of MUC5AC in stomach
7) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Abstract Doc Link 12843612 Disease Relevance 0.09 Pain Relevance 0.13
Postnatal changes and effects of glucocorticoid on MUC5AC mRNA expression in the rat stomach.
Gene_expression (expression) of MUC5AC in stomach
8) Confidence 0.67 Published 2003 Journal Biol. Pharm. Bull. Section Title Doc Link 12843612 Disease Relevance 0.09 Pain Relevance 0.14
Unlike mucous neck cells in the normal mucosa, TFF2 cells in the healing ulcer coexpressed MUC5AC (but little MUC6) in the neck and also coexpressed pepsinogen.
Gene_expression (coexpressed) of MUC5AC in neck associated with ulcers
9) Confidence 0.36 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912238 Disease Relevance 1.28 Pain Relevance 0.11
These glands were lined with cells expressing MUC5AC, a marker of foveolar cells (Figure 5c).
Gene_expression (expressing) of MUC5AC in glands
10) Confidence 0.36 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912238 Disease Relevance 0.57 Pain Relevance 0
MUC5AC cells decreased in the neck and was present mainly in the foveolae (Figure 6c), similar to the location in the normal fundic mucosa.
Gene_expression (present) of MUC5AC in neck
11) Confidence 0.31 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912238 Disease Relevance 1.15 Pain Relevance 0
The expression of MUC1 and MUC5AC is associated with the progression of PanIN.
Gene_expression (expression) of MUC5AC
12) Confidence 0.18 Published 2006 Journal Rinsho Byori Section Abstract Doc Link 16789413 Disease Relevance 0.45 Pain Relevance 0.08
In this study, we examined the association between the expression of MUC1, MUC2, MUC5AC, and E-cadherin, and the pathological changes from normal pancreatic tissue to invasive ductal carcinoma(IDC).
Gene_expression (expression) of MUC5AC associated with ductal carcinoma
13) Confidence 0.18 Published 2006 Journal Rinsho Byori Section Abstract Doc Link 16789413 Disease Relevance 0.44 Pain Relevance 0.08
Immunohistochemical study of the association between the progression of pancreatic ductal lesions and the expression of MUC1, MUC2, MUC5AC, and E-cadherin.
Gene_expression (expression) of MUC5AC
14) Confidence 0.18 Published 2006 Journal Rinsho Byori Section Title Doc Link 16789413 Disease Relevance 0.51 Pain Relevance 0.08
Goblet cells of the appendix express both MUC2 and MUC5AC mucins but primary ovarian mucinous tumors only express MUC5AC.
Gene_expression (express) of MUC5AC in appendix associated with cancer
15) Confidence 0.13 Published 2005 Journal World J Surg Oncol Section Body Doc Link PMC1182398 Disease Relevance 1.25 Pain Relevance 0.08
Goblet cells of the appendix express both MUC2 and MUC5AC mucins but primary ovarian mucinous tumors only express MUC5AC.
Gene_expression (express) of MUC5AC in appendix associated with cancer
16) Confidence 0.13 Published 2005 Journal World J Surg Oncol Section Body Doc Link PMC1182398 Disease Relevance 1.30 Pain Relevance 0.08
METHODS: We immunohistochemically examined expression patterns of MUC1, MUC2, MUC5AC, cytokeratin 7 (CK7), and CK20 in BilIN, IPN-B, and ICC in 110 cases of hepatolithiasis.
Spec (examined) Gene_expression (expression) of MUC5AC
17) Confidence 0.10 Published 2006 Journal J. Hepatol. Section Body Doc Link 16360234 Disease Relevance 0.18 Pain Relevance 0
METHODS: We immunohistochemically examined expression patterns of MUC1, MUC2, MUC5AC, cytokeratin 7 (CK7), and CK20 in BilIN, IPN-B, and ICC in 110 cases of hepatolithiasis.
Spec (examined) Gene_expression (patterns) of MUC5AC
18) Confidence 0.10 Published 2006 Journal J. Hepatol. Section Body Doc Link 16360234 Disease Relevance 0.18 Pain Relevance 0
In rat DHE cells, beta-casomorphin-7 increased the expression of rat mucin (rMuc)2 and rMuc3 but not rMuc1, rMuc4, and rMuc5AC.
Gene_expression (expression) of rMuc5AC
19) Confidence 0.01 Published 2006 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 16357059 Disease Relevance 0 Pain Relevance 0.34

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