INT111601

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Context Info
Confidence 0.24
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CTNNA1) aging (CTNNA1) cell adhesion (CTNNA1)
structural molecule activity (CTNNA1) plasma membrane (CTNNA1) cytoplasm (CTNNA1)
CTNNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
interstitial cystitis 8 95.82 Very High Very High Very High
Disease Link Frequency Relevance Heat
Interstitial Cystitis 8 95.82 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The general pattern of gene expression in IC and APF-treated cells suggested a less proliferative phenotype, with increased expression of E-cadherin, phosphoribosylpyrophosphate synthetase-associated protein 39, and SWI/SNF complex 170-kDa subunit, and decreased expression of vimentin, alpha2-integrin, alpha1-catenin, cyclin D1, and jun N-terminal kinase 1; these findings were confirmed for the structural gene products (E-cadherin, vimentin, alpha2-integrin, and alpha-catenin) by immunohistochemistry.
Negative_regulation (decreased) of Gene_expression (expression) of alpha1-catenin associated with interstitial cystitis
1) Confidence 0.24 Published 2003 Journal Physiol. Genomics Section Abstract Doc Link 12847144 Disease Relevance 0.58 Pain Relevance 0.58

General Comments

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