INT111790

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Context Info
Confidence 0.22
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk) plasma membrane (Npr1) intracellular (Npr1)
Penk (Rattus norvegicus)
Npr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 4 100.00 Very High Very High Very High
Somatostatin 3 100.00 Very High Very High Very High
Enkephalin 3 100.00 Very High Very High Very High
substance P 1 98.76 Very High Very High Very High
Dynorphin 1 97.40 Very High Very High Very High
Substantia nigra 1 84.96 Quite High
projection neuron 1 78.32 Quite High
Neurotransmitter 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 4 100.00 Very High Very High Very High
Dyskinesias 2 86.40 High High
Syndrome 1 85.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No change in cortical cholecystokinin (CCK), ENK, glutamic acid decarboxylase (GAD) and somatostatin (SRIF) expression, in striatal GAD, SRIF, nitric oxide synthase (NOS) and guanylate cyclase expression, and in thalamic CCK, GAD and thyrotropin-releasing hormone expression was found.
ENK Neg (No) Regulation (change) of Gene_expression (expression) of guanylate cyclase associated with generalized anxiety disorder, somatostatin, enkephalin and cholecystokinin
1) Confidence 0.22 Published 2003 Journal Neurosci. Lett. Section Abstract Doc Link 12865138 Disease Relevance 0.56 Pain Relevance 0.86

General Comments

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