INT111813

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Context Info
Confidence 0.12
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CREM, CRH) cell differentiation (CREM) extracellular space (CRH)
extracellular region (CRH) nucleus (CREM) DNA binding (CREM)
CREM (Homo sapiens)
CRH (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 2 98.64 Very High Very High Very High
Kinase C 1 98.48 Very High Very High Very High
antidepressant 2 82.48 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Forskolin (an activator of adenylate cyclase), but not phorbol 12-myristate 13-acetate (an activator of protein kinase C), ca. 3-fold increased reporter gene activity, which confirms the critical role of the cAMP-responsive element in regulation of the CRH gene.
cAMP-responsive element Regulation (role) of Regulation (regulation) of CRH gene associated with kinase c
1) Confidence 0.12 Published 2002 Journal Pol J Pharmacol Section Abstract Doc Link 12866730 Disease Relevance 0 Pain Relevance 0.30

General Comments

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