INT111820

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Context Info
Confidence 0.42
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 10
Total Number 11
Disease Relevance 10.63
Pain Relevance 3.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Fdps) nucleolus (Fdps) peroxisome (Fdps)
nucleus (Fdps) cytoplasm (Fdps)
Fdps (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 43 100.00 Very High Very High Very High
cva 48 99.56 Very High Very High Very High
Inflammation 20 99.02 Very High Very High Very High
Mcgill questionnaire 1 95.68 Very High Very High Very High
Hyperalgesia 10 93.52 High High
dorsal root ganglion 2 91.04 High High
Inflammatory mediators 2 87.00 High High
cytokine 4 84.36 Quite High
bradykinin 4 83.80 Quite High
Central nervous system 6 61.92 Quite High
Disease Link Frequency Relevance Heat
Pain 45 100.00 Very High Very High Very High
Disease 115 99.68 Very High Very High Very High
Cv General 3 Under Development 4 99.56 Very High Very High Very High
Chronic Disease 15 99.12 Very High Very High Very High
INFLAMMATION 22 99.02 Very High Very High Very High
Disseminated Intravascular Coagulation 152 98.96 Very High Very High Very High
Injury 20 98.42 Very High Very High Very High
Toxicity 4 97.76 Very High Very High Very High
Hyperalgesia 12 93.52 High High
Ganglion Cysts 2 91.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to accommodate FPs' schedules, three of the five interviews were held in the early evening, and two in the morning.
Positive_regulation (accommodate) of FPs
1) Confidence 0.42 Published 2004 Journal BMC Fam Pract Section Body Doc Link PMC535864 Disease Relevance 0.20 Pain Relevance 0
The FPs were much more involved and updated concerning the medical care of these patients.
Positive_regulation (updated) of FPs
2) Confidence 0.23 Published 2010 Journal BMC Fam Pract Section Body Doc Link PMC2984454 Disease Relevance 0 Pain Relevance 0
Insufficient time or routines at the HC and organisational boundaries were working conditions that could prevent FPs from retaining the initiative.
Positive_regulation (prevent) of FPs
3) Confidence 0.23 Published 2010 Journal BMC Fam Pract Section Body Doc Link PMC2984454 Disease Relevance 0.34 Pain Relevance 0.05
Consultants rely on DNs to arrange future FP visits for both acute conditions and chronic diseases and to manage some diseases independently, contacting the FPs when necessary.
Positive_regulation (contacting) of FPs associated with disease and chronic disease
4) Confidence 0.23 Published 2010 Journal BMC Fam Pract Section Body Doc Link PMC2984454 Disease Relevance 0.20 Pain Relevance 0
Results showed a significant increase in the scores on the CAS for Pain Affect and the FPS in the demented patients compared to the control group.
Positive_regulation (increase) of FPS associated with pain
5) Confidence 0.19 Published 2003 Journal Psychiatry Section Abstract Doc Link 12868293 Disease Relevance 1.81 Pain Relevance 1.20
Activation of GPR92/LPA5 by FPP increases IP production, cAMP levels, and Ca2+ levels in a concentration-dependent manner.
Positive_regulation (increases) of FPP
6) Confidence 0.18 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996792 Disease Relevance 0.74 Pain Relevance 0.63
A report by Yin and colleagues [24] states that FPP was not effective in recruiting beta arrestin in a GPR92 expression system.
Neg (not) Positive_regulation (effective) of FPP
7) Confidence 0.15 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996792 Disease Relevance 0.55 Pain Relevance 0.48
FDPs, which serve as a marker of plasmin activation, are elevated in 85–100% patients with DIC, but the specificity of high levels of FDPs is limited and many other conditions, such as trauma, recent surgery, inflammation or venous thrombo-embolism, are associated with elevated FDPs.
Positive_regulation (elevated) of FDPs associated with inflammation, injury, disseminated intravascular coagulation and cva
8) Confidence 0.13 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434752 Disease Relevance 1.65 Pain Relevance 0.23
Therefore, it is not surprising that the elevated levels of D-dimer and FDPs in the model guinea pigs may reflect the hematological toxicity of the leptospiral LPS, but not strong enough to cause any detectable DIC.
Positive_regulation (elevated) of FDPs associated with toxicity and disseminated intravascular coagulation
9) Confidence 0.10 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434752 Disease Relevance 1.55 Pain Relevance 0
FDPs, which serve as a marker of plasmin activation, are elevated in 85–100% patients with DIC, but the specificity of high levels of FDPs is limited and many other conditions, such as trauma, recent surgery, inflammation or venous thrombo-embolism, are associated with elevated FDPs.
Positive_regulation (activation) of FDPs associated with inflammation, injury, disseminated intravascular coagulation and cva
10) Confidence 0.09 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434752 Disease Relevance 1.79 Pain Relevance 0.21
FDPs, which serve as a marker of plasmin activation, are elevated in 85–100% patients with DIC, but the specificity of high levels of FDPs is limited and many other conditions, such as trauma, recent surgery, inflammation or venous thrombo-embolism, are associated with elevated FDPs.
Positive_regulation (elevated) of FDPs associated with inflammation, injury, disseminated intravascular coagulation and cva
11) Confidence 0.09 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434752 Disease Relevance 1.80 Pain Relevance 0.21

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