INT111888

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Akt1, Oprm1) plasma membrane (Akt1, Oprm1) transport (Akt1)
aging (Akt1) enzyme binding (Akt1) carbohydrate metabolic process (Akt1)
Akt1 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 5 99.24 Very High Very High Very High
opioid receptor 1 98.40 Very High Very High Very High
antagonist 4 95.60 Very High Very High Very High
agonist 1 93.44 High High
Potency 2 92.80 High High
Spinal cord 3 85.76 High High
analgesia 1 67.44 Quite High
Analgesic 1 37.60 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies suggest a role for G-protein receptor kinases (GRKs) and dynamin (DYN), but not signaling proteins (e.g., G(ialpha2)), in regulation of muOR density following opioid treatment.
kinases Regulation (role) of Regulation (regulation) of muOR associated with opioid
1) Confidence 0.04 Published 2003 Journal Synapse Section Abstract Doc Link 12872295 Disease Relevance 0 Pain Relevance 0.77

General Comments

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