INT112004

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Context Info
Confidence 0.50
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.56
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
lymphocyte 2
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Antinociceptive 5 97.60 Very High Very High Very High
Inflammation 38 97.48 Very High Very High Very High
cytokine 35 96.44 Very High Very High Very High
intrathecal 2 95.68 Very High Very High Very High
Spinal cord 2 93.76 High High
Pain 1 91.28 High High
Neuropathic pain 3 76.16 Quite High
fibrosis 2 68.56 Quite High
withdrawal 1 59.28 Quite High
Piles 1 48.64 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 41 97.48 Very High Very High Very High
Pain 1 91.28 High High
Hypoxia 3 89.28 High High
Radiation Sickness 1 87.80 High High
Injury 1 82.08 Quite High
Cancer 38 81.88 Quite High
Toxicity 18 81.44 Quite High
Nociception 4 78.48 Quite High
Carcinoma 1 77.68 Quite High
Neuropathic Pain 3 76.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This supported the hypothesis that the therapeutic effect of IL-2 gene was related to IL-2 protein expression.
Positive_regulation (related) of Negative_regulation (effect) of IL-2 gene
1) Confidence 0.50 Published 2003 Journal Gene Ther. Section Abstract Doc Link 12883536 Disease Relevance 0.58 Pain Relevance 0.69
and inhibition of IL-1 and IL-2 induced lymphocyte stimulation [reviewed in [52]].
Positive_regulation (induced) of Negative_regulation (inhibition) of IL-2 in lymphocyte
2) Confidence 0.08 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1464387 Disease Relevance 0.99 Pain Relevance 0.13
In the absence of mitogens, both MTB and CW treatment of PBMC led to decreased IL-2 levels compared to untreated PBMC (Figure 5A).
Positive_regulation (led) of Negative_regulation (decreased) of IL-2
3) Confidence 0.08 Published 2010 Journal BMC Immunol Section Body Doc Link PMC2858026 Disease Relevance 0 Pain Relevance 0.26

General Comments

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