INT11201

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Context Info
Confidence 0.18
First Reported 1992
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.43
Pain Relevance 2.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pfkm) kinase activity (Pfkm) cytoplasm (Pfkm)
Anatomy Link Frequency
endothelial cells 1
spinal cord 1
Pfkm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 7 99.68 Very High Very High Very High
Kinase C 5 94.16 High High
Hyperalgesia 3 90.64 High High
intrathecal 5 90.52 High High
Inflammation 8 89.44 High High
tolerance 8 88.60 High High
Morphine 14 88.20 High High
spinal dorsal horn 1 83.36 Quite High
Inflammatory stimuli 1 80.24 Quite High
Analgesic 1 76.80 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 7 89.44 High High
Hyperalgesia 4 60.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The constitutive expression and inducibility of UDP-GT isozyme(s) for 1-naphthol glucuronidation was also clearly demonstrated in Kupffer and endothelial cells.
Gene_expression (expression) of isozyme in endothelial cells
1) Confidence 0.18 Published 1992 Journal Biochem. Pharmacol. Section Abstract Doc Link 1540226 Disease Relevance 0 Pain Relevance 0.15
Expression of the gamma isozyme was not affected by the oligonucleotides.
Gene_expression (Expression) of gamma isozyme
2) Confidence 0.02 Published 2002 Journal Neuroscience Section Abstract Doc Link 12123688 Disease Relevance 0 Pain Relevance 1.53
Protein kinase Cbeta antisense oligodeoxynucleotide had no significant effect on the membrane-associated activities of protein kinase Calpha and protein kinase Cgamma, but decreased the activities of both protein kinase CbetaI and protein kinase CbetaII and the expression of protein kinase Cbeta isozyme in the spinal cord.
Gene_expression (expression) of isozyme in spinal cord associated with spinal cord
3) Confidence 0.00 Published 2006 Journal Neuroscience Section Abstract Doc Link 16360284 Disease Relevance 0.43 Pain Relevance 0.65

General Comments

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