INT112014

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Context Info
Confidence 0.34
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.07
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand2) nucleus (Hand2) DNA binding (Hand2)
protein complex (Hand2) transcription factor binding (Hand2)
Hand2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 61 100.00 Very High Very High Very High
cytokine 42 99.96 Very High Very High Very High
cINOD 4 99.40 Very High Very High Very High
antagonist 40 86.36 High High
Arthritis 1 85.04 High High
chemokine 8 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 64 100.00 Very High Very High Very High
Airway Remodeling 2 99.08 Very High Very High Very High
Atherosclerosis 67 98.80 Very High Very High Very High
Asthma 43 96.48 Very High Very High Very High
Hyperlipidemia 2 96.40 Very High Very High Very High
Apoptosis 6 93.08 High High
Atherosclerotic Plaque 28 86.44 High High
Arthritis 1 85.04 High High
Hyperplasia 13 82.48 Quite High
Disease 16 63.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indomethacin inhibited both Th1 and Th2 responses, although the nonsteroidal anti-inflammatory drug suppressed the former more effectively than the latter.
Negative_regulation (inhibited) of Regulation (responses) of Th2 associated with inflammation and cinod
1) Confidence 0.34 Published 2003 Journal J Pharm Sci Section Abstract Doc Link 12884258 Disease Relevance 0.33 Pain Relevance 0.37
Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

Background

Negative_regulation (diminishes) of Regulation (modulation) of Th2 associated with inflammation and cytokine
2) Confidence 0.20 Published 2010 Journal Respir Res Section Title Doc Link PMC2914735 Disease Relevance 0.98 Pain Relevance 0.45
Th2 responses are also recognised in
Negative_regulation (recognised) of Regulation (responses) of Th2
3) Confidence 0.06 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.75 Pain Relevance 0.04

General Comments

This test has worked.

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