INT112018

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Context Info
Confidence 0.22
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1) nucleoplasm (Hand1) enzyme binding (Hand1)
DNA binding (Hand1) cytoplasm (Hand1) nucleolus (Hand1)
Hand1 (Mus musculus)
IgG2a (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 4 88.04 High High
Arthritis 1 62.24 Quite High
transdermal 7 50.00 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 87.84 High High
Body Weight Changes 2 85.76 High High
Immunization 44 84.76 Quite High
Arthritis 1 62.24 Quite High
Influenza Virus Infection 35 59.88 Quite High
Body Weight 1 50.16 Quite High
Infection 2 23.60 Low Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On day 21, anti-OVA IgG2a and interferon-gamma as an indicator of Th1 responses and anti-OVA IgG1 and interleukin-10 as that of Th2 responses were measured.
Th1 Binding (indicator) of IgG2a
1) Confidence 0.22 Published 2003 Journal J Pharm Sci Section Abstract Doc Link 12884258 Disease Relevance 0.30 Pain Relevance 0.32
This is significant because the ratio of IgG1/IgG2a is correlated with immune responses that are predominantly T helper type 2 (Th2) or T helper type 1 (Th1), suggesting a strong bias towards Th2 responses with the MN route and Th1 with the IM route.
Th1 Binding (ratio) of IgG2a
2) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2651574 Disease Relevance 0.54 Pain Relevance 0

General Comments

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