INT112025

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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1) nucleoplasm (Hand1) intracellular (Il10)
enzyme binding (Hand1) DNA binding (Hand1) cytoplasm (Hand1)
Anatomy Link Frequency
T cell 1
Hand1 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 100.00 Very High Very High Very High
Multiple sclerosis 121 98.12 Very High Very High Very High
cINOD 4 86.72 High High
Arthritis 6 66.00 Quite High
Central nervous system 28 61.60 Quite High
Inflammation 45 6.88 Low Low
imagery 22 5.00 Very Low Very Low Very Low
rheumatoid arthritis 17 5.00 Very Low Very Low Very Low
Demyelination 5 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 221 98.12 Very High Very High Very High
INFLAMMATION 51 86.52 High High
Autoimmune Disease 43 75.52 Quite High
Arthritis 1 66.00 Quite High
Reprotox - General 3 1 29.64 Quite Low
Disease 101 11.68 Low Low
Recurrence 27 5.00 Very Low Very Low Very Low
Sprains And Strains 26 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 18 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
production post partum as compared to the third trimester and myelin protein specific T cell lines derived from subjects in the third trimester produced more IL10 [113], while Al-Shammri et al. found that six of the eight MS patients' ex vivo stimulated PBMCs showed a distinct shift from a Th2 cytokine bias (IL4 and IL10) during pregnancy, towards a Th1 cytokine bias (IFN?
Th1 Binding (bias) of IL10 in T cell associated with multiple sclerosis and cytokine
1) Confidence 0.15 Published 2011 Journal Biol Sex Differ Section Body Doc Link PMC3022636 Disease Relevance 0.25 Pain Relevance 0.22
On day 21, anti-OVA IgG2a and interferon-gamma as an indicator of Th1 responses and anti-OVA IgG1 and interleukin-10 as that of Th2 responses were measured.
Th1 Binding (indicator) of interleukin-10
2) Confidence 0.09 Published 2003 Journal J Pharm Sci Section Abstract Doc Link 12884258 Disease Relevance 0.31 Pain Relevance 0.33

General Comments

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