INT112062

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
prefrontal 2
Kcnk2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dopamine receptor 1 100.00 Very High Very High Very High
Glutamate 1 98.12 Very High Very High Very High
Nucleus accumbens 2 95.00 High High
gABA 1 75.00 Quite High
Dopamine 1 75.00 Quite High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Schizophrenia 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used in situ hybridization histochemistry to assess expression of dopamine receptors (D1R, D2R and D3R), neurotensin, proenkephalin and glutamate decarboxylase-67 (GAD67) in the prefrontal cortex, striatum, and/or nucleus accumbens in adult rats with neonatal ventral hippocampal (VH) lesions and in control animals after acute and chronic treatment with antipsychotic drugs clozapine and haloperidol.
Positive_regulation (assess) of Gene_expression (expression) of D1R in prefrontal associated with nucleus accumbens, glutamate and dopamine receptor
1) Confidence 0.01 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 12887421 Disease Relevance 0.14 Pain Relevance 0.22

General Comments

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