INT112068

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Context Info
Confidence 0.58
First Reported 2003
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.60
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (GIF) extracellular space (GIF) extracellular region (GIF)
Anatomy Link Frequency
nerve 1
pancreas 1
GIF (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 3 98.88 Very High Very High Very High
Nerve growth factor 4 98.20 Very High Very High Very High
cytokine 38 97.64 Very High Very High Very High
substance P 1 95.96 Very High Very High Very High
Analgesic 3 95.08 Very High Very High Very High
Pain score 1 94.48 High High
Inflammation 34 94.12 High High
fibrosis 2 92.80 High High
anesthesia 1 92.00 High High
Pain 7 86.72 High High
Disease Link Frequency Relevance Heat
Injury 8 99.06 Very High Very High Very High
Pancreatitis 2 96.40 Very High Very High Very High
Pain 8 94.20 High High
INFLAMMATION 34 94.12 High High
Subacute Combined Degeneration 1 94.08 High High
Fibrosis 2 92.80 High High
Cognitive Disorder 90 90.96 High High
Frailty 1 90.96 High High
Bites And Stings 10 89.36 High High
Gliosis 1 87.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In wound exudate, 19 out of 20 mediators were reliably detected including IL-1 beta, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-17, TNFalpha, INF gamma, G-CSF, GM-CSF, MCP-1 and MIP-1 beta, nerve growth factor (NGF), prostaglandin E2 (PG-E2) and substance P.
Gene_expression (detected) of INF in nerve associated with nerve growth factor, injury and substance p
1) Confidence 0.58 Published 2008 Journal Journal of visualized experiments : JoVE Section Abstract Doc Link 19078937 Disease Relevance 1.27 Pain Relevance 0.84
The presence of alternative patterns of cytokine production has been well established in several pathological conditions and is usually referred to as TH1 cells that produce IL-2 and INF-gamma but not IL-4 and TH2 cells that produce IL-4 but not IL-2/IFN-gamma.
Neg (not) Gene_expression (produce) of INF associated with cytokine
2) Confidence 0.58 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.07 Pain Relevance 0.17
This condition can be accountable for cobalamin deficiency, as the pancreas is the only source of intrinsic factor in cats.
Gene_expression (source) of intrinsic factor in pancreas
3) Confidence 0.51 Published 2003 Journal J Vet Med A Physiol Pathol Clin Med Section Abstract Doc Link 12887621 Disease Relevance 0.95 Pain Relevance 0.35
Yet, to get a clearer picture of intrinsic motivation, one needs to understand that it has been defined by contrast to extrinsic motivation:
Gene_expression (motivation) of intrinsic
4) Confidence 0.08 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0.09 Pain Relevance 0
Competence-based models of intrinsic motivation
Gene_expression (motivation) of intrinsic
5) Confidence 0.08 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
Morphological models of intrinsic motivation
Gene_expression (motivation) of intrinsic
6) Confidence 0.08 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0.16 Pain Relevance 0
Knowledge-based models of intrinsic motivation
Gene_expression (motivation) of intrinsic
7) Confidence 0.08 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
However, in certain application contexts, their intrinsic openness is a weakness.
Gene_expression (openness) of intrinsic
8) Confidence 0.08 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0.06 Pain Relevance 0

General Comments

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