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Context Info
Confidence 0.40
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dlg2, Grin2a) transport (Grin2a) locomotion (Grin2a)
cytoplasm (Dlg2)
Dlg2 (Mus musculus)
Grin2a (Mus musculus)
Pain Link Frequency Relevance Heat
spinal dorsal horn 1 96.20 Very High Very High Very High
Lasting pain 4 84.68 Quite High
nMDA receptor 3 80.92 Quite High
Peripheral nerve injury 1 78.00 Quite High
Acute pain 1 67.84 Quite High
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 100.00 Very High Very High Very High
Pain 5 84.68 Quite High
Nervous System Injury 1 77.12 Quite High
Nociception 1 70.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Targeted disruption of the PSD-93 gene reduces not only surface NR2A and NR2B expression but also NMDAR-mediated excitatory postsynaptic currents and potentials, without affecting surface AMPA receptor expression or its synaptic function, in the regions mentioned above.
Negative_regulation (disruption) of PSD-93 gene Negative_regulation (reduces) of Gene_expression (expression) of NR2A associated with targeted disruption
1) Confidence 0.40 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12890763 Disease Relevance 0.49 Pain Relevance 0.57

General Comments

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